2782-40-3

Basic information

• Product Name: N-butylbenzamide
• Synonyms: N-butylbenzamide;Butylbenzamide
• CAS NO: 2782-40-3
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.2429
• EINECS: 220-485-4
• Mol File: 2782-40-3.mol
• Article Data: 258

Chemical Properties

• Boiling Point: 340.4°Cat760mmHg
• Flash Point: 201.6°C
• Appearance: /
• Density: 0.988g/cm³
• Vapor Pressure: 8.62E-05mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: N-butylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-butylbenzamide(2782-40-3)
• EPA Substance Registry System: N-butylbenzamide(2782-40-3)

Safety Data

• Hazardous Substances Data: 2782-40-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 3313, 1994 DOI: 10.1016/S0040-4039(00)76894-8

InChI:InChI=1/C11H15NO/c1-2-3-9-12-11(13)10-7-5-4-6-8-10/h4-8H,2-3,9H2,1H3,(H,12,13)

Upstream product

• 123206-90-6 N-n-propyl-N-n-butylbenzamide 
• 106262-09-3 7,8-didehydro-4,5-epoxy-17-methyl-(5α,6α)-morphinan-3,6-diol 3,6-dibenzoate 
• 117067-47-7 N-(1-Benzotriazol-1-yl-butyl)-benzamide 
• 10026-13-8 phosphorus pentachloride 
• 109-73-9 N-butylamine 
• 100-51-6 benzyl alcohol 
• 93-58-3 benzoic acid methyl ester 
• 21710-99-6 2-butyl-3-phenyloxarizidine 
• 100-52-7 benzaldehyde 
• 611-73-4 Benzoylformic acid 
• 3858-78-4 n-butylamine hydrochloride 
• 640-60-8 toluene-4-sulfonic acid phenyl ester 
• 111-36-4 n-butyl isocyanide 
• 100-42-5 styrene 

Downstream Products

• 15421-91-7 N-(n-butyl)benzamidine 
• 41182-88-1 N-butyl-benzimidoyl chloride 
• 51874-22-7 N-Butyl-benzimidoyl bromide 
• 109-65-9 1-bromo-butane 
• 493-77-6 2,4,6-triphenyl-1,3,5-triazine 
• 100-47-0 benzonitrile 
• 1515-72-6 N-butylphthalimide 
• 1485-70-7 N-benzylbenzamide 
• 1759-68-8 N-benzoylcyclohexylamine 
• 5440-69-7 N-isopropylbenzamide 
• 10575-94-7 N-benzyl-N-nitrosobenzamide 
• 14657-86-4 N,N-dipropylbenzamide 
• 776-75-0 N-benzoylpiperidine 
• 40999-33-5 N-Butyl-benzimidic acid 2,2,2-trifluoro-1-phenyl-1-trifluoromethyl-ethyl ester 

Relevant articles and documents

NaOTs-promoted transition metal-free C-N bond cleavage to form C-X (X = N, O, S) bonds

Multifunctional transformation of amide C-N bond cleavage is reported. The protocol applies to benzamide, thioamide, alcohols, and mercaptan under similar reaction conditions catalyzed by NaOTs. It is noteworthy that NaOTs can not only be recycled and reused for up to three cycles without significant loss in catalytic activity, but also catalyze gram-grade reactions. This study provides a novel solution with mild conditions and a simple procedure for transformation of multiple amides.

CuO-decorated magnetite-reduced graphene oxide: a robust and promising heterogeneous catalyst for the oxidative amidation of methylarenes in waterviabenzylic sp3C-H activation

A magnetite-reduced graphene oxide-supported CuO nanocomposite (rGO/Fe3O4-CuO) was preparedviaa facile chemical method and characterized by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), UV-vis spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive spectroscopy (EDS), Brunauer-Emmett-Teller (BET) analysis, vibrating-sample magnetometry (VSM), and thermogravimetric (TG) analysis. The catalytic activity of the rGO/Fe3O4-CuO nanocomposite was probed in the direct oxidative amidation reaction of methylarenes with free amines. Various aromatic and aliphatic amides were prepared efficiently at room temperature from cheap raw chemicals usingtert-butyl hydroperoxide (TBHP) as a “green” oxidant and low-toxicity TBAI in water. This method combines the oxidation of methylarenes and amide bond formation into a single operation. Moreover, the synthesized nanocomposites can be separated from the reaction mixtures using an external magnet and reused in six consecutive runs without a noticeable decrease in the catalytic activity.

N,O-Benzyl Protection of Structurally Varied Amines and Phenols Using Wells-Dawson Heteropolyacid Catalyst

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