354529-99-0Relevant articles and documents
Synthesis method of terminal olefin type compound
-
Paragraph 0081; 0083; 0084, (2018/09/21)
The invention discloses a synthesis method of a terminal olefin type compound. The synthesis method comprises the following steps: taking a phosphorus ylide compound as a raw material and carbon dioxide as a C1 synthon in an organic solvent; reacting in the presence of a reducing agent to prepare the terminal olefin type compound, wherein the mole ratio of the phosphorus ylide compound to the reducing agent is 1 to (1 to 6) and the pressure of carbon dioxide is 1 to 3atm. The synthesis method disclosed by the invention has the advantages of convenience for operation, moderate conditions, widesubstrate applicable range and high efficiency; the defects in the prior art are filled; the synthesis method takes the carbon dioxide as synthon and carbon dioxide can be effectively absorbed so thata greenhouse effect is effectively prevented.
Thermal retro-aldol reaction using fluorous ether F-626 as a reaction medium
Fukuyama, Takahide,Kawamoto, Takuji,Okamura, Takahiro,Denichoux, Aurelien,Ryu, Ilhyong
experimental part, p. 2193 - 2196 (2010/10/21)
A high-boiling, fluorous-organic hybrid ether, F-626, was tested for use in thermal retro-aldol reactions and found to be an excellent reaction medium in view of the ease of separation from the product by fluorous/organic biphasic treatment. The recovered F-626 can be readily reused for subsequent runs.
A direct synthesis of α-(hydroxymethyl) and α-alkyl-vinyl alkyl ketones
Kra?em, Jihène Ben,Ayed, Ta?cir Ben,Amri, Hassen
, p. 7077 - 7079 (2007/10/03)
Reaction of 2,4-diketoesters 3a-c with aqueous formaldehyde using potassium carbonate solution as base affords the corresponding α-methylene-β-hydroxyalkanones 4a-c which provide a route to α,β-unsaturated alkyl ketones 6a-e via coupling of α-acetoxymethy