367-11-3 Usage
Chemical Properties
colourless liquid
Uses
Different sources of media describe the Uses of 367-11-3 differently. You can refer to the following data:
1. 1,2-Difluorobenzene is used in electrochemical analysis of transition metal complexes. 1,2-difluorobenzene is also a potent inhibitor of NMDA receptor.
2. 1,2-Difluorobenzene(1,2-DFB) has been used to study the mechanism of dissociation of o-, m- and p-difluorobenzene ions by threshold photoelectron photoion coincidence spectroscopy. It has been used to study the room temperature adsorption of 1,2-DFB, 1,2-dichlorobenzene and 1,2-dibromobenzene on Si(100)2x1 by X-ray photoelectron spectroscopy and temperature programmed desorption. It is used as solvent in electrochemical studies on transition metal complexes. It is also applied as a solvent useful for electrochemical studies on transition metal complexes.
Definition
ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 2.
General Description
1,2-Difluorobenzene undergoes defluorination under very mild conditions by H2 in the presence of NaOAc over rhodium pyridylphosphine and bipyridyl complexes tethered on a silica-supported palladium catalyst.
Check Digit Verification of cas no
The CAS Registry Mumber 367-11-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,6 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 367-11:
(5*3)+(4*6)+(3*7)+(2*1)+(1*1)=63
63 % 10 = 3
So 367-11-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H4F2/c7-5-3-1-2-4-6(5)8/h1-4H
367-11-3Relevant articles and documents
Shaw,Hyman
, p. 1563 (1969)
Three-step regioselective synthesis of 2,3-difluorohalobenzenes using tetrafluoroethylene and buta-1,3-diene as starting building blocks
Egorov, M. P.,Lipkind, M. B.,Nefedov, O. M.,Volchkov, N. V.
, p. 925 - 932 (2021/06/07)
The gas-phase copyrolysis of tetrafluoroethylene and buta-1,3-diene in a flow tube reactor at 490–510 °C gives 3,3,4,4-tetrafluorocyclohex-1-ene, which is selectively converted to 1-bromo- or 1-chloro-2,3-difluorobenzene via intermediate steps of halogenation and dehydrohalogenation.
Two-step regioselective synthesis of 1,2-difluorobenzenes from chlorotrifluoroethylene and buta-l,3-dienes
Lipkind, M. B.,Nefedov, O. M.,Volchkov, N. V.
, p. 68 - 75 (2020/04/21)
The gas-phase copyrolysis of chlorotrifluoroethylene with buta-1,3-diene, penta-1,3-diene, or isoprene in a flow reactor at 440–480°C gave 4-chloro-4,5,5-trifluorocyclohex-1-enes. The latter treated with aqueous KOH under condition of phase-transfer catalysis were selectively converted into 1,2-difluorobenzene, 2,3-difluorotoluene, or 3,4-difluorotoluene.
