462-95-3 Usage
Chemical Properties
colourless liquid
Uses
Different sources of media describe the Uses of 462-95-3 differently. You can refer to the following data:
1. Diethoxymethane (DEM) is offered by Eastman Chemical
Company as a cost-effective replacement solvent for monoglyme (1,2-
dimethoxyethane) and methylal. The DEM diether is stable under alkaline
conditions, but can be cleaved by strong acids. Diethoxymethane can be used as a
chemical intermediate in many organic synthesis reactions. Diethoxymethane is
useful as a solvent in lithium batteries with nonaqueous electrolytes, as a solvent
for polymeric materials, and as a fuel additive. As a chemical intermediate DEM
can act as an ethoxymethylating reagent for alcohols and phenols and serve as a
source for formaldehyde in organic synthesis.
2. Diethoxymethane may be used as a substitute solvent to dichloromethane and toluene in the O-alkylation of different phenols in the presence of phase transfer catalysts (PTCs).
Synthesis Reference(s)
Synthetic Communications, 25, p. 3939, 1995 DOI: 10.1080/00397919508011470
General Description
A colorless volatile liquid with an agreeable odor. Less dense than water. Flash point below 10°F. Vapors heavier than air. May be narcotic in high concentrations. Used as a solvent and in the manufacture of cosmetics.
Air & Water Reactions
Highly flammable. Soluble in water.
Reactivity Profile
DIETHOXYMETHANE, an acetal, is incompatible with strong oxidizing agents and acids. Breaks down to formaldehyde and ethanol in acidic solutions.
Health Hazard
Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution.
Fire Hazard
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility
Highlyflammable
Safety Profile
Moderately toxic by
ingestion. Flammable when exposed to heat
or flame; can react vigorously with oxidizers.
When heated to decomposition it emits
acrid smoke and irritating fumes.
Check Digit Verification of cas no
The CAS Registry Mumber 462-95-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 2 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 462-95:
(5*4)+(4*6)+(3*2)+(2*9)+(1*5)=73
73 % 10 = 3
So 462-95-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H12O2/c1-3-6-5-7-4-2/h3-5H2,1-2H3
462-95-3Relevant articles and documents
Thumm,B.A.,Tryon,S.
, p. 2999 - 3002 (1964)
Enhanced Hydrogenation of Carbon Dioxide to Methanol by a Ruthenium Complex with a Charged Outer-Coordination Sphere
Erickson, Jeremy D.,Linehan, John C.,Preston, Andrew Z.,Wiedner, Eric S.
, p. 7419 - 7423 (2020/07/21)
We report the hydrogenation of CO2 to MeOH by a Ru(triphos) catalyst containing a cationic tetraalkylammonium moiety in the outer coordination sphere. This catalyst affords higher TON and TOF values for MeOH than isostructural catalysts with neutral phosphine ligands. Kinetic data from operando NMR spectroscopy studies indicate the improvement in MeOH production arises from a 12-fold enhancement in the rate of hydrogenation of the transient formaldehyde intermediate. These results provide insight into the catalyst characteristics that promote MeOH formation.
Effect of the Nature of the Catalyst on Catalytic Activity and Selectivity in the Formaldehyde Hydrogenation
Tarasov
, p. 1670 - 1674 (2018/09/13)
The effect the nature of the carrier and supported metal on the activity and selectivity of the catalyst in the reaction of formaldehyde hydrogenation to methanol is studied. The formation of such oxygenates as ethanol, formic acid, and diethyl formal is observed. It is found that ethanol forms on Fe-containing alloyed catalyst, while formic acid forms on the catalysts containing Au. Thermodynamic calculations are performed for a series of side reactions that confirm the formation of the resulting oxygenates.
