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538-37-4

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538-37-4 Usage

Chemical Properties

[95%] in Benzene - 10% w/v

Uses

Different sources of media describe the Uses of 538-37-4 differently. You can refer to the following data:
1. In solutions with inert solvents such as chloroform, carbon tetrachloride, benzene and ether for the phosphorylation of nucleosides and amino acids.
2. Please note that this product is shipped in a cooler

Check Digit Verification of cas no

The CAS Registry Mumber 538-37-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,3 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 538-37:
(5*5)+(4*3)+(3*8)+(2*3)+(1*7)=74
74 % 10 = 4
So 538-37-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H14ClOP/c15-17(16,11-13-7-3-1-4-8-13)12-14-9-5-2-6-10-14/h1-10H,11-12H2

538-37-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Dibenzylphosphoryl Chloride

1.2 Other means of identification

Product number -
Other names DIBENZYLPHOSPHORYL CHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:538-37-4 SDS

538-37-4Relevant articles and documents

Novel antibody-antibiotic conjugate eliminates intracellular S. aureus

Lehar, Sophie M.,Pillow, Thomas,Xu, Min,Staben, Leanna,Kajihara, Kimberly K.,Vandlen, Richard,DePalatis, Laura,Raab, Helga,Hazenbos, Wouter L.,Hiroshi Morisaki,Kim, Janice,Park, Summer,Darwish, Martine,Lee, Byoung-Chul,Hernandez, Hilda,Loyet, Kelly M.,Lupardus, Patrick,Fong, Rina,Yan, Donghong,Chalouni, Cecile,Luis, Elizabeth,Khalfin, Yana,Plise, Emile,Cheong, Jonathan,Lyssikatos, Joseph P.,Strandh, Magnus,Koefoed, Klaus,Andersen, Peter S.,Flygare, John A.,Wah Tan, Man,Brown, Eric J.,Mariathasan, Sanjeev

, p. 323 - 328 (2015)

Staphylococcus aureus is considered to be an extracellular pathogen. However, survival of S. aureus within host cells may provide a reservoir relatively protected from antibiotics, thus enabling long-term colonization of the host and explaining clinical f

Investigating the role of the geminal dimethyl groups of coenzyme A: Synthesis and studies of a didemethyl analogue

Vogel, Kurt W.,Stark, Lucy M.,Mishra, Pranab K.,Yang, Wei,Drueckhammer, Dale G.

, p. 2451 - 2460 (2000)

An analogue 2 of coenzyme A (CoA) has been prepared in which the geminal methyl groups are replaced with hydrogens. An NMR titration study was conducted and shifts in frequency of protons in the pantetheine portion of the molecule upon titration of the adenine base were observed as has been previously reported with CoA. These studies indicate that the geminal dimethyl groups are not essential for adoption of a partially folded conformation in solution. Based on 1H-1H coupling constants, the distribution of conformations about the carbon-carbon bonds in the region of the methyl deletion were estimated. The results suggest that the conformer distribution is similar to that of CoA, but with small increases in population of the anti conformers. A simple model compound containing the didemethyl pantoamide moiety was prepared and subjected to similar conformational analysis. The coupling constants and predicted conformer distribution were almost identical to that of the CoA analogue, indicating that the conformer distribution is controlled by local interactions and not influenced by interactions between distant parts of the CoA molecule. The acetyl derivative of 2 was a fairly good substrate for the acetyl-CoA utilizing enzymes carnitine acetyltransferase, chloramphenicol acetyltransferase, and citrate synthase, with 1.3- to 10-fold increased K(m) values and 2.5- to 11-fold decreases in V(max). The combined results indicate that the geminal dimethyl groups of CoA have modest effects on function and minimal effects on conformation. Copyright (C) 2000 Elsevier Science Ltd.

PANTETHEINE DERIVATIVES AND USES THEREOF

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Paragraph 2121, (2020/06/19)

The present disclosure relates to compounds of Formula (I), (II), or (II'): (I), (II), (II'), and pharmaceutically acceptable salts or solvates thereof. The present disclosure also relates to pharmaceutical compositions comprising the compounds and therapeutic and diagnostic uses of the compounds and pharmaceutical compositions.

METHODS AND COMPOSITIONS FOR PRODRUG FORMS OF SPECTINOMYCIN AND SPECTINAMIDE ANALOGS

-

Paragraph 0589-0590; 0602; 0609; 0615; 0621, (2020/06/01)

In one aspect, the disclosure relates to substituted spectinomycin analogs, including substituted aminomethyl spectinomycin analogs and substituted spectinamide analogs, with increased tolerability and safety, including improved tolerability to parenteral

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