577-72-0Relevant articles and documents
Design, synthesis, and biological evaluation of quinazoline derivatives as dual HDAC1 and HDAC6 inhibitors for the treatment of cancer
Chen, Jinying,Sang, Zitai,Jiang, Youjun,Yang, Chao,He, Linhong
, p. 232 - 241 (2018/11/02)
Fifty-eight quinazoline-based compounds were designed and synthesized based on the structural optimizations from the lead compound 23bb in an attempt to search for more potent dual HDAC1 and HDAC6 inhibitors. Among them, 32c (HDAC1, IC50?=?31.1
2 - Amino - 4 - acetamido anisole novel synthesis process (by machine translation)
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Paragraph 0059-0060; 0072; 0081, (2018/03/01)
The present invention provides a novel 2 - amino - 4 - acetamido anisole synthesis process, the usage of palladium bi-metal catalysts and the palladium/carbon catalyst to replace Rany - Ni catalyst, to the anisole on the nitro-selective catalytic hydrogenation, which not only reduces use Rany - Ni catalyst of post-industrial risks, while at the same time, the resulting 2 - amino - 4 - acetyl anisole purity higher, greater yield. (by machine translation)
Method for synthesizing 3-amino-4-methoxy acetanilide by binary alloy catalysis
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Paragraph 0027; 0028; 0029; 0030; 0031; 0032; 0033-0054, (2017/04/29)
The invention relates to a method for synthesizing 3-amino-4-methoxy acetanilide by catalytically hydrogenising 3-nitro-4-methoxy acetanilide (NMA) with a nano copper/ silver binary alloy catalyst, and belongs to the field of nano catalysis. The reaction
