58656-98-7

Basic information

• Product Name: T-BUTYL 4-FLUOROBENZOATE
• Synonyms: T-BUTYL 4-FLUOROBENZOATE;TERT-BUTYL 4-FLUOROBENZOATE;Benzoic acid, 4-fluoro-, 1,1-diMethylethyl ester;tert-Butyl4-fluorobenzoate97%
• CAS NO: 58656-98-7
• Molecular Formula: C₁₁H₁₃FO₂
• Molecular Weight: 196.22
• Mol File: 58656-98-7.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 51-52/0.4mm
• Flash Point: 94.3°C
• Appearance: /
• Density: 1.083g/cm³
• Vapor Pressure: 0.0464mmHg at 25°C
• Refractive Index: 1.484
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: T-BUTYL 4-FLUOROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: T-BUTYL 4-FLUOROBENZOATE(58656-98-7)
• EPA Substance Registry System: T-BUTYL 4-FLUOROBENZOATE(58656-98-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 58656-98-7(Hazardous Substances Data)

Usage

General Description

T-BUTYL 4-FLUOROBENZOATE is a chemical compound that belongs to the ester class of compounds. It is a colorless to pale yellow liquid with a faint fruity odor. This chemical is commonly used as a fragrance ingredient in personal care products and perfumes. It is also used as an intermediate for the synthesis of various pharmaceuticals and agrochemicals. T-BUTYL 4-FLUOROBENZOATE is considered to have low toxicity, but it should be handled with caution and proper safety measures should be followed when working with this compound.

InChI:InChI=1/C11H13FO2/c1-11(2,3)14-10(13)8-4-6-9(12)7-5-8/h4-7H,1-3H3

Upstream product

• 540-80-7 tert.-butylnitrite 
• 456-03-1 1-(4-fluorophenyl)propan-1-one 
• 456-22-4 4-Fluorobenzoic acid 
• 75-65-0 tert-butyl alcohol 
• 75-91-2 tert.-butylhydroperoxide 
• 459-22-3 4-fluorophenylacetonitrile 
• 24424-99-5 di-tert-butyl dicarbonate 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 1765-93-1 4-fluoroboronic acid 
• 214360-58-4 2-(4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 120363-13-5 tert-butyl 4-iodobenzoate 
• 201230-82-2 carbon monoxide 
• 865-48-5 sodium t-butanolate 
• 403-43-0 4-fluorobenzoyl chloride 

Downstream Products

• 94930-28-6 N-<4'-(tert-butoxycarbonyl)phenyl>-3-pyrrolidinol 
• 95017-91-7 1-<4-(tert-butoxycarbonyl)phenyl>-4-hydroxypiperidine 
• 403-43-0 4-fluorobenzoyl chloride 
• 1068160-34-8 4-octylaminobenzoic acid tert-butyl ester 
• 99916-98-0 tert-butyl 4-(2-amino-ethylamino)-benzoate 
• 1195951-20-2 C₂₀H₁₈Cl₂N₂O₃ 
• 935252-64-5 4-[4-(2-aminoethyl)phenoxy]benzoic acid, tert-butyl ester 
• 187669-28-9 tert-butyl 4-(piperazin-1-yl)benzoate 
• 179487-85-5 ethyl 1-(4-(tertbutoxycarbonyl)phenyl)piperidine-4-carboxylate 
• 866002-10-0 4-[4-(5-Trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-benzoic acid tert-butyl ester 
• 733785-78-9 tert-butyl 4-(2-(piperidin-1-yl)ethylamino)benzoate 
• 131010-66-7 (S)-2-[4-(2-Amino-4-oxo-4,4b,5,7,8,8a,9,10-octahydro-3H-1,3,6,10-tetraaza-phenanthren-6-yl)-benzoylamino]-pentanedioic acid diethyl ester 
• 1211306-46-5 cis-5,11-methylenetetrahydro-5-deazahomofolate 
• 95017-90-6 diethyl N-<4-<7-(2-acetamido-5-deaza-4(3H)-oxo-6,7,8,9-tetrahydropyrido<3,4-g>pteridino)>benzoyl>-L-glutamate 

Relevant articles and documents

Enolate-Based Regioselective Anti-Beckmann C-C Bond Cleavage of Ketones

The Baeyer-Villiger or Beckmann rearrangements are established methods for the cleavage of ketone derivatives under acidic conditions, proceeding for unsymmetrical precursors selectively at the more substituted site. However, the fragmentation regioselectivity cannot be switched and fragmentation at the less-substituted terminus is so far not possible. We report here that the reaction of ketone enolates with commercial alkyl nitrites provides a direct and regioselective way of fragmenting ketones into esters and oximes or ω-hydroxyimino esters, respectively. A comprehensive study of the scope of this reaction with respect to ketone classes and alkyl nitrites is presented. Control over the site of cleavage is gained through regioselective enolate formation by various bases. Oxidation of kinetic enolates of unsymmetrical ketones leads to the otherwise unavailable "anti-Beckmann"cleavage at the less-substituted side chain, while cleavage of thermodynamic enolates of the same ketones represents an alternative to the Baeyer-Villiger oxidation or the Beckmann rearrangement under basic conditions. The method is suited for the transformation of natural products and enables access to orthogonally reactive dicarbonyl compounds.

Ribavirin semi-antigen and artificial antigen and its preparation method and application (by machine translation)

The invention relates to ribavirin semi-antigen and artificial antigen and its preparation method and application. The ribavirin semi-antigen having a structure of formula (I) or formula (II) as shown: The ribavirin artificial antigen is represented by t

A fluorobenzene imidazole impurity E preparation method

The invention discloses a fluorobenzene imidazole impurity E preparation method. Characterized in that in order to para-benzoic acid as the starting material, after chlorination reaction, esterification reaction, a Friedel-crafts acylation reaction, hydro