599-70-2

Basic information

• Product Name: Ethyl phenyl sulfone
• Synonyms: ETHYL PHENYL SULPHONE;ETHYL PHENYL SULFONE;ETHYLSULFONYLBENZENE;Benzene,(ethylsulfonyl)-;Ethanesulfonyl-benzene;Phenyl ethyl sulfone;Sulfone, ethyl phenyl;(ethylsulphonyl)benzene
• CAS NO: 599-70-2
• Molecular Formula: C₈H₁₀O₂S
• Molecular Weight: 170.23
• EINECS: 209-972-2
• Product Categories: Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;Organic Building Blocks;Sulfones;Sulfur Compounds
• Mol File: 599-70-2.mol

Chemical Properties

• Melting Point: 35-40 °C(lit.)
• Boiling Point: 103 °C / 1mmHg
• Flash Point: >230 °F
• Appearance: White to light yellow/Crystalline Powder
• Density: 1.14
• Vapor Pressure: 0.000926mmHg at 25°C
• Refractive Index: 1.5090 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 2045095
• CAS DataBase Reference: Ethyl phenyl sulfone(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl phenyl sulfone(599-70-2)
• EPA Substance Registry System: Ethyl phenyl sulfone(599-70-2)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 599-70-2(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystalline powder

Uses

Ethyl phenyl sulfone may be used in the preparation of (±)-α-multistriatin.

General Description

Density of ethyl phenyl sulfone is 1.1410g/cm3 at 20°C.

InChI:InChI=1/C8H10O2S/c1-2-11(9,10)8-6-4-3-5-7-8/h3-7H,2H2,1H3

Upstream product

• 74-96-4 ethyl bromide 
• 873-55-2 sodium benzenesulfonate 
• 64-67-5 diethyl sulfate 
• 60-29-7 diethyl ether 
• 1912-28-3 methyl ethanesulfonate 
• 1912-30-7 ethyl ethanesulfonate 
• 6927-20-4 phenyl ethanesulfonate 
• 4500-58-7 2-ethylthiophenol 
• 20803-96-7 2-benzenesulphonylpropionic acid 
• 75-03-6 ethyl iodide 
• 98-09-9 benzenesulfonyl chloride 
• 108-88-3 toluene 
• 622-38-8 Ethyl phenyl sulfide 
• 201230-82-2 carbon monoxide 

Downstream Products

• 2976-31-0 1-(ethylsulfonyl)-3-nitrobenzene 
• 59807-95-3 1,1-Diphenyl-2-(benzolsulfonyl)propen 
• 59807-96-4 1,1-Diphenyl-2-(benzolsulfonyl)propan-1-ol 
• 68470-89-3 2-Phenylsulfonyleicosan-3-on 
• 27839-91-4 1-phenyl-2-(phenylsulfonyl)-propan-1-one 
• 91787-35-8 1-phenylsulphonyl-1-trimethylsilylethane 
• 148311-94-8 1-hydroxy-3-phenylsulphonyl-1-(triphenylsilyl)-butanes 
• 1829-40-9 hexaphenyldisiloxanne 
• 791-31-1 triphenylhydroxysilane 
• 119472-51-4 [(1-Methylcyclopent-3-en-1-yl)sulfonyl]benzene 
• 140396-97-0 (1-Trifluoromethanesulfonyl-ethanesulfonyl)-benzene 
• 88257-46-9 Trimethyl-((E)-1-phenethyl-propenyloxy)-silane 
• 119204-46-5 (3S,4S)-2-Benzenesulfonyl-3-trimethylsilanyl-octan-4-ol 
• 118353-48-3 [(1R,2S,4R)-6-Benzenesulfonyl-1-((1S,3R)-3-[1,3]dithian-2-yl-1-methoxy-butyl)-2-methoxy-4-methyl-heptyloxy]-tert-butyl-dimethyl-silane 

Relevant articles and documents

Hydroformylation of Vinyl Sulfones and Sulfoxides Catalyzed by a Zwitterionic Rhodium Complex. A Diastereoselective Process

The hydroformylation of unsaturated sulfones and sulfoxides catalyzed by η6-C6H5B-Ph3Rh+ (1,5-COD) (1) was achieved in excellent yield and regiocontrol, with exclusive formation of branched-chain aldehydes.In the case of phenyl vinyl sulfoxide, evidence is presented for stereoselectivity in the reaction.

On the Unexpected Cathodic Electrodimerization of Phenyl Vinyl Sulphone in slightly Protic Media: the Formation of 1,4-Bisphenylsulphonylbut-2-ene

Phenyl vinyl sulphone exhibits unusual cathodic behaviour in organic media containing a small excess of a proton donor such as acetic acid or phenol; both the saturated sulphone and an unsaturated dimer are isolated, the formation of which may be explained by hydrogen atom transfer between the organic free radicals formed at the interface.

Surface decorated magnetic nanoparticles with Mn-porphyrin as an effective catalyst for oxidation of sulfides

Mn-porphyrin complex was anchored coordinatively to silica-coated surface of magnetic nanoparticles (SMNP). Afterward, a heterogeneous nanocatalyst (Fe3O4@SiO2-MnTCPP) has been characterized by Fourier transform infrared (FT-IR), ultraviolet-visible (UV-vis) spectroscopy, powder X-ray diffraction (XRD), scanning electron microscopy (SEM), vibrating sample magnetometry (VSM), thermogravimetric analysis (TGA), and transmission electron microscope (TEM). A thermal stability up to around 350°C was verified for prepared nanocatalyst based on thermogravimetric analysis. Finally, the catalytic performance of magnetically recoverable Mn-catalyst was exploited in the green oxidation of different sulfides with urea hydrogen peroxide (UHP) in the presence of imidazole as co-catalyst in ethanol under heterogeneous conditions. The eco-friendly property of ethanol strongly induced us to employ it as the reaction solvent in this oxidation system. Complete conversion (≥99) of sulfides to the corresponding sulfoxide or sulfones was obtained for ethyl phenyl sulfide, phenyl vinyl sulfide, diallyl sulfide, thiocyanatoethane, 2-ethyl mercaptoethanol and tetrahydrothiophene. Moreover, the recovered catalysts keep constant conversion yield up to at least three cycles.

Method for synthesizing aryl alkyl sulfone compound by promoting oxidation of aryl alkyl thioether compound through visible light

The invention discloses a method for synthesizing an aryl alkyl sulfone compound by promoting oxidation of an aryl alkyl thioether compound through visible light. The method comprises the following steps of: performing one-pot reaction on an aryl alkyl thioether compound and sodium trifluoromethanesulfinate in a diethylene glycol dibutyl ether solution system under the conditions of oxygen-containing atmosphere and 385-390 nm purple light irradiation to generate the aryl alkyl sulfone compound. The method has the advantages of mild conditions, simple operation, environmental protection, easilyavailable raw materials, excellent compatibility of substrate functional groups, high reaction yield and the like.

Highly Selective Hydrogenation of C═C Bonds Catalyzed by a Rhodium Hydride

Under mild conditions (room temperature, 80 psi of H2) Cp*Rh(2-(2-pyridyl)phenyl)H catalyzes the selective hydrogenation of the C═C bond in α,β-unsaturated carbonyl compounds, including natural product precursors with bulky substituents in the β position and substrates possessing an array of additional functional groups. It also catalyzes the hydrogenation of many isolated double bonds. Mechanistic studies reveal that no radical intermediates are involved, and the catalyst appears to be homogeneous, thereby affording important complementarity to existing protocols for similar hydrogenation processes.

Mechanically Strong Heterogeneous Catalysts via Immobilization of Powderous Catalysts to Porous Plastic Tablets

Main observation and conclusion: We describe a practical and general protocol for immobilization of heterogeneous catalysts to mechanically robust porous ultra-high molecular weight polyethylene tablets using inter-facial Lifshitz-van der Waals Interactions. Diverse types of powderous catalysts, including Cu, Pd/C, Pd/Al2O3, Pt/C, and Rh/C have been immobilized successfully. The immobilized catalysts are mechanistically robust towards stirring in solutions, and they worked well in diverse synthetic reactions. The immobilized catalyst tablets are easy to handle and reused. Moreover, the metal leaching of immobilized catalysts was reduced significantly.

Method for catalytically oxidizing thioether to sulphone

The invention discloses a method for catalytically oxidizing thioether to sulphone. In this method, thioether is added to an ethanol solution. H2 O2 The nitrogen-nitrogen co-doped graphene catalyst is reacted at room temperature to obtain sulfone. The method is simple and convenient to operate, environment-friendly in reaction process, low in production cost, free of metal catalysts, free of secondary pollution, mild in reaction conditions, low in catalyst consumption, high and product yield and the like.

Electrochemical oxygenation of sulfides with molecular oxygen or water: Switchable preparation of sulfoxides and sulfones

A practical and eco-friendly method for the controllable aerobic oxygenation of sulfides by electrochemical catalysis was developed. The switchable preparation of sulfoxides and sulfones was effectively controlled by reaction time, in which both molecular oxygen and water can be used as the oxygen source under catalyst and external oxidant-free conditions. The electrochemical protocol features a broad substrate scope and excellent site selectivity and is successfully applied to the modification of some sulfide-containing pharmaceuticals and their derivatives. This journal is

Synergistic cooperative effect of CF3SO2Na and bis(2-butoxyethyl)ether towards selective oxygenation of sulfides with molecular oxygen under visible-light irradiation

A safe, practical and eco-friendly method for the switchable synthesis of sulfoxides and sulfones through visible-light-initiated oxygenation of sulfides at ambient temperature under transition-metal-, additives-free and minimal solvent conditions. The synergistic catalytic efforts between CF3SO2Na and 2-butoxyethyl ether represents the key promoting factor for the reaction. This journal is

Flow Electrosynthesis of Sulfoxides, Sulfones, and Sulfoximines without Supporting Electrolytes

An efficient electrochemical flow process for the selective oxidation of sulfides to sulfoxides and sulfones and of sulfoxides toN-cyanosulfoximines has been developed. In total, 69 examples of sulfoxides, sulfones, andN-cyanosulfoximines have been synthesized in good to excellent yields and with high current efficiencies. The synthesis was assisted and facilitated through a supporting electrolyte-free, fully automated electrochemical protocol that highlights the advantages of flow electrolysis.