636-78-2Relevant articles and documents
Kinetics and mechanism of the oxidation of water soluble porphyrin Fe IIITPPS with hydrogen peroxide and the peroxomonosulfate ion
Lente, Gabor,Fabian, Istvan
, p. 4268 - 4275 (2007)
The overall six-electron oxidation of water soluble porphyrin Fe IIITPPS by hydrogen peroxide and peroxomonosulfate ion was studied by the stopped-flow method with UV-vis detection. A three-step consecutive reaction was observed with two intermediates: FeIIITPPS → Int1 → Int2 → products. The products were identified as the iron(iii) complex of the biliverdin analog formed from TPPS and 4-sulfobenzoic acid. All the rate constants with both oxidizing agents were determined. Intermediate Int1 is proposed to be the species (TPPS+)FeIVO. Although no unambiguous proposal for the structure of Int2 can be made, it is most probably the product of the four-electron oxidation of the original FeIIITPPS, contains an iron-oxo center and has a dissociable proton with a pK of around 3.1. In spite of the protolytic equilibria occuring in the pH region 2-4, the kinetic observations do not show pH dependence. The Royal Society of Chemistry.
Continuous production method of benzoic acid derivative
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Paragraph 0032-0035, (2021/11/14)
The invention relates to the technical field of preparation of benzoic acid derivatives. The invention particularly relates to a continuous production method of a benzoic acid derivative. The continuous reaction device is characterized by comprising a small-diameter sleeve, wherein the small-diameter sleeve is sleeved with a large-diameter sleeve, and a small pipeline is arranged between the small-diameter sleeve and the large-diameter sleeve, and a plurality of small holes are arranged on the small pipeline. The small-diameter casing is rotated, the large-diameter casing is fixed, and the reaction liquid composed of the nitric acid and the toluene derivative is between a small-diameter casing pipe and a large-diameter casing pipe.
Aryl and alkyl sulfonic acid compounds as well as construction method adopting inorganic sulfur salt and application
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Paragraph 0046-0049; 0080-0083, (2020/09/16)
The invention discloses aryl and alkyl sulfonic acid compounds as shown in a formula (1) and a synthesis method thereof. The method comprises the following step: aromatic iodine and an inorganic sulfur source or alkyl bromide and an inorganic sulfur source as reaction raw materials react in a solvent under the action of alkali, a catalyst or an additive to obtain a series of aryl and alkyl sulfonic acid compounds. According to the method, the aryl and alkyl sulfonic acid compounds are constructed in one step by taking an inorganic sulfur reagent as a sulfur source, so that the defect of the mode in which the aryl and alkyl sulfonic acid compounds are synthesized by taking concentrated sulfuric acid, chlorosulfonic acid or sulfur dioxide gas and the like as sulfonating reagents in the priorart is avoided. The aryl and alkyl sulfonic acid compounds developed by the invention can be used for synthesizing aryl and alkyl sulfonic acid drug analogues.