7028-48-0

Basic information

• Product Name: phenylacetaldehyde oxime
• Synonyms: phenylacetaldehyde oxime;phenylacetaldoxime;2-Phenylethanone oxime;Benzeneacetaldehyde oxime;(Z)-phenylacetaldoxime
• CAS NO: 7028-48-0
• Molecular Formula: C₈H₉NO
• Molecular Weight: 135.16316
• EINECS: 230-309-8
• Mol File: 7028-48-0.mol
• Article Data: 39

Chemical Properties

• Boiling Point: 272.444 °C at 760 mmHg
• Flash Point: 159.077 °C
• Appearance: /
• Density: 1.004 g/cm³
• Vapor Pressure: 0.00297mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: phenylacetaldehyde oxime(CAS DataBase Reference)
• NIST Chemistry Reference: phenylacetaldehyde oxime(7028-48-0)
• EPA Substance Registry System: phenylacetaldehyde oxime(7028-48-0)

Safety Data

• Hazardous Substances Data: 7028-48-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 16, p. 91, 1986 DOI: 10.1080/00397918608057693

InChI:InChI=1/C8H9NO/c10-9-7-6-8-4-2-1-3-5-8/h1-5,7,10H,6H2

Upstream product

• 102-96-5 (2-nitroethenyl)benzene 
• 5873-91-6 phenyldithioacetic acid 
• 64-04-0 phenethylamine 
• 122-78-1 phenylacetaldehyde 
• 60-29-7 diethyl ether 
• 100-52-7 benzaldehyde 
• 103-82-2 phenylacetic acid 
• 51451-05-9 chloroacetaldoxime 
• 591-51-5 phenyllithium 
• 60-12-8 2-phenylethanol 
• 536-74-3 phenylacetylene 
• 300-57-2 allylbenzene 
• 5153-67-3 nitrostyrene 
• 860554-18-3 N-(1-amino-2-phenyl-ethyl)-benzamide 

Downstream Products

• 13972-58-2 trans-Bis-[2-phenyl-1-acetoxy->-azoethan-N.N'-dioxid 
• 161151-98-0 3,5-dibenzyl-4,5-dihydroisoxazole 
• 184166-22-1 3-Benzyl-5-(4-methoxy-benzyl)-4,5-dihydro-isoxazole 
• 184166-21-0 3-Benzyl-5-(2-methoxy-benzyl)-4,5-dihydro-isoxazole 
• 110911-04-1 2a-Methyl-6-phenyl-2,2a,2b,3-tetrahydro-1H,6H-4-oxa-5,6a-diaza-cyclobuta[a]pentalene 
• 3278-14-6 N-phenethylbenzamide 
• 877-95-2 methyl-N-(benzyl-methyl)-formamide 
• 52250-50-7 1-phenyl-3,4-dihydroisoquinoline 
• 23069-99-0 N-(2-phenylethyl)formamide 
• 110911-02-9 C₁₇H₂₆N₂OSi 
• 116298-52-3 (2aR,2bR,6R)-2a-Methyl-6-phenyl-2,2a,2b,3-tetrahydro-1H,6H-4-oxa-5,6a-diaza-cyclobuta[a]pentalene 
• 116298-53-4 (2aR,2bS,6R)-2a-Methyl-6-phenyl-2,2a,2b,3-tetrahydro-1H,6H-4-oxa-5,6a-diaza-cyclobuta[a]pentalene 
• 110911-03-0 (2-Methyl-2-vinyl-azetidin-1-yl)-phenyl-acetaldehyde oxime 
• 103979-34-6 N-acetylphenylacetamidoxime 

Relevant articles and documents

Chemoenzymatic one-pot reaction from carboxylic acid to nitrile: Via oxime

We report a new chemoenzymatic cascade starting with aldehyde synthesis by carboxylic acid reductase (CAR) followed by chemical in situ oxime formation. The final step to the nitrile is catalyzed by aldoxime dehydratase (Oxd). Full conversions of phenylacetic acid and hexanoic acid were achieved in a two-phase mode.

SO2F2-Mediated one-pot cascade process for transformation of aldehydes (RCHO) to cyanamides (RNHCN)

A simple, mild and practical cascade process for the direct conversion of aldehydes to cyanamides was developed featuring a wide substrate scope and great functional group tolerability. This method allows for transformations of readily available, inexpensive, and abundant aldehydes to highly valuable cyanamides in a pot, atom, and step-economical manner with a green nitrogen source. This protocol will serve as a robust tool for the installation of the cyanamide moiety in various complicated molecules.

Cascade Process for Direct Transformation of Aldehydes (RCHO) to Nitriles (RCN) Using Inorganic Reagents NH2OH/Na2CO3/SO2F2 in DMSO

A simple, mild, and practical process for direct conversion of aldehydes to nitriles was developed feathering a wide substrate scope and great functional group tolerability (52 examples, over 90% yield in most cases) using inorganic reagents (NH2OH/Na2CO3/SO2F2) in DMSO. This method allows for transformations of readily available, inexpensive, and abundant aldehydes to highly valuable nitriles in a pot, atom, and step-economical manner without transition metals. This protocol will serve as a robust tool for the installation of cyano-moieties to complicated molecules.