7163-50-0 Usage
Description
4-methylbenzoylformic acid, also known as p-toluyloxyacetic acid, is a chemical compound with the molecular formula C9H8O3. It is a derivative of benzoylformic acid and belongs to the class of aromatic carboxylic acids. This white crystalline solid is sparingly soluble in water and has a melting point of around 98-100°C. It is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and agrochemicals. Additionally, it exhibits anti-inflammatory and analgesic properties and has been studied for its potential application in the treatment of certain medical conditions. Careful handling is advised, as it can be harmful if ingested or inhaled, and may cause skin and eye irritation.
Uses
Used in Pharmaceutical Industry:
4-methylbenzoylformic acid is used as a building block for the synthesis of various pharmaceuticals due to its versatile chemical structure and reactivity.
Used in Agrochemical Industry:
4-methylbenzoylformic acid is used as a precursor in the production of agrochemicals, contributing to the development of effective pest control agents.
Used in Medical Treatment:
4-methylbenzoylformic acid is used as a potential therapeutic agent for certain medical conditions, leveraging its anti-inflammatory and analgesic properties to alleviate symptoms and improve patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 7163-50-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,6 and 3 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7163-50:
(6*7)+(5*1)+(4*6)+(3*3)+(2*5)+(1*0)=90
90 % 10 = 0
So 7163-50-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H8O3/c1-6-2-4-7(5-3-6)8(10)9(11)12/h2-5H,1H3,(H,11,12)
7163-50-0Relevant articles and documents
Evidence for the Generation of α-Carboxy-α-hydroxy-p-xylylene from p-(Bromomethyl)mandelate by Mandelate Racemase
Lin, David T.,Powers, Vincent M.,Reynolds, Laure J.,Whitman, Christian P.,Kozarich, John W.,Kenyon, George L.
, p. 323 - 326 (1988)
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Silyl Cyanopalladate-Catalyzed Friedel-Crafts-Type Cyclization Affording 3-Aryloxindole Derivatives
Ece, Hamdiye,Tange, Yuji,Yurino, Taiga,Ohkuma, Takeshi
, p. 935 - 939 (2021/02/22)
3-Aryloxindole derivatives were synthesized through a Friedel-Crafts-type cyclization. The reaction was catalyzed by a trimethylsilyl tricyanopalladate complex generated in situ from trimethylsilyl cyanide and Pd(OAc) 2. Wide varieties of diethyl phosphates derived from N -arylmandelamides were converted almost quantitatively into oxindoles. When N, N -dibenzylamide was used instead of an anilide substrate, a benzo-fused δ-lactam was obtained. An oxindole product was subjected to substitution reactions to afford 3,3-diaryloxindoles with two different aryl groups.
Iridium-catalyzed stereoselective [3+2] annulation of α-oxocarboxylic acids with 1,3-dienes
Yabe, Ryota,Ebe, Yusuke,Nishimura, Takahiro
supporting information, p. 5917 - 5920 (2021/06/18)
The stereoselective annulation of α-oxocarboxylic acids with 1,3-dienes proceeded in the presence of a hydroxoiridium catalyst to give α-hydroxy-γ-lactones in good yields with high 3,5-transrelative stereochemistry. The use of a chiral diene ligand for a cationic iridium complex enabled asymmetric annulation with high enantioselectivity.
