7465-88-5

Basic information

• Product Name: N-Phenyl-4-methoxybenzamide
• Synonyms: 4-Methoxy-N-phenylbenzamide;N-Phenyl-4-methoxybenzamide;p-Anisanilide;BenzaMide, 4-Methoxy-N-phenyl-
• CAS NO: 7465-88-5
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.26
• Mol File: 7465-88-5.mol
• Article Data: 208

Chemical Properties

• Boiling Point: 301.5°C at 760 mmHg
• Flash Point: 136.1°C
• Appearance: /
• Density: 1.181g/cm³
• Vapor Pressure: 0.00105mmHg at 25°C
• Refractive Index: 1.619
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: N-Phenyl-4-methoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Phenyl-4-methoxybenzamide(7465-88-5)
• EPA Substance Registry System: N-Phenyl-4-methoxybenzamide(7465-88-5)

Safety Data

• Hazardous Substances Data: 7465-88-5(Hazardous Substances Data)

Usage

General Description

N-Phenyl-4-methoxybenzamide, also known as 4-methoxy-N-phenylbenzamide, is a chemical compound with the molecular formula C14H13NO2. It is a white crystalline solid that is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. N-Phenyl-4-methoxybenzamide has been reported to possess anti-inflammatory and analgesic properties, making it a potential candidate for the development of new medicines. Additionally, this compound has been studied for its potential use in the treatment of neurodegenerative diseases and cancer. However, further research is needed to fully understand the biological activities and potential therapeutic applications of N-Phenyl-4-methoxybenzamide.

InChI:InChI=1/C14H13NO2/c1-17-13-9-7-11(8-10-13)14(16)15-12-5-3-2-4-6-12/h2-10H,1H3,(H,15,16)

Upstream product

• 79-37-8 oxalyl dichloride 
• 60-29-7 diethyl ether 
• 10147-61-2 (Z)-(4-methoxyphenyl)(phenyl)methanone oxime 
• 59101-33-6 N-benzoyl-O-(4-methoxy-benzoyl)-hydroxylamine 
• 100-07-2 4-methoxy-benzoyl chloride 
• 62-53-3 aniline 
• 100-66-3 methoxybenzene 
• 698-16-8 benzohydroximoyl chloride 
• 114050-46-3 N-(4-methoxybenzoyloxy)-pyridine-2(1H)-thione 
• 40499-78-3 [4-(4-methoxybenzoyl)-2-oxido-1,2,5-oxadiazol-2-ium-3-yl]-(4-methoxyphenyl)methanone 
• 10147-60-1 (4-methoxyphenyl)phenylmethanone oxime 
• 10026-13-8 phosphorus pentachloride 
• 7647-01-0 hydrogenchloride 
• 141583-51-9 (Z)-methyl 4-methoxy-N-phenylbenzimidate 

Downstream Products

• 1151-93-5 4-(N,N-dimethylamino)-4'-methoxybenzophenone 
• 104689-69-2 (4-(diethylamino)phenyl)(4-methoxyphenyl)methanone 
• 68823-22-3 2-(4-methoxy-phenyl)-4,6-dioxo-3,5-diphenyl-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 154822-32-9 3-hydroxy-3-(pyridin-4-yl)-5-methoxy-2-phenyl-2,3-dihydro-1H-isoindol-1-one 
• 28281-58-5 7-methoxyisobenzofuran-1(3H)-one 
• 100990-66-7 4-methoxy-N-(4-(4-methoxybenzamido)phenyl)-N-phenylbenzamide 
• 26060-23-1 4-methoxy-N-phenylthiobenzamide 
• 221632-75-3 3-hydroxy-3-(pyridin-3-yl)-5-methoxy-2-phenyl-2,3-dihydro-1H-isoindol-1-one 
• 154822-28-3 3-hydroxy-3-(pyridin-2-yl)-5-methoxy-2-phenyl-2,3-dihydro-1H-isoindol-1-one 
• 259817-06-6 ethyl 2-diazo-3-[N-(4-methoxybenzoyl)-N-phenylamino]-3-oxopropanoate 
• 246525-75-7 3-(4-Methoxyphenyl)-5-methoxy-3H-isobenzofuran-1-one 
• 111752-96-6 N-(α-anilino-p-methoxybenzylidene)-N'-methyl-N'-phenylthiourea 
• 405166-59-8 3-hydroxy-5-methoxy-2,3-diphenyl-2,3-dihydro-isoindol-1-one 
• 890979-57-4 acetic acid 4-(4-methoxybenzoylamino)phenyl ester 

Relevant articles and documents

Novel Conjugated s-Tetrazine Derivatives Bearing a 4H-1,2,4-Triazole Scaffold: Synthesis and Luminescent Properties

A series of new symmetrical s-tetrazine derivatives, coupled via a 1,4-phenylene linkage with a 4H-1,2,4-triazole ring, were obtained. The combination of these two rings in an extensively coupled system has significant potential applications, mainly in op

Nickel-Catalyzed Reductive Cross-Coupling of N-Acyl and N-Sulfonyl Benzotriazoles with Diverse Nitro Compounds: Rapid Access to Amides and Sulfonamides

Herein we report a Ni-catalyzed reductive transamidation of conveniently available N-acyl benzotriazoles with alkyl, alkenyl, and aryl nitro compounds, which afforded various amides with good yields and a broad substrate scope. The same catalytic reaction conditions were also applicable for N-sulfonyl benzotriazoles, which could undergo smooth reductive coupling with nitroarenes and nitroalkanes to afford the corresponding sulfonamides.

Visible-light-induced direct construction of amide bond from carboxylic acids with amines in aqueous solution

A novel visible-light-promoted N-acylation for the synthesis of amides from easily available carboxylic acids with amines in the presence of I2 within 2.5 h in aqueous solution has been developed. Using sunlight as the visible light source greatly reduces the cost of experiments and produces almost no toxic effects. Hence, this study provides an alternative catalytic system for the construction of a wide range of amides with readily available materials. Moreover, the strategy was successfully applied in the preparation of N-(3-(2,6-dimethoxyphenoxy)-7-nitroquinoxalin-2-yl)benzohydrazide, which displayed a signification anti-proliferation effect on A549, MCF-7 and HCT116 cell lines.