756-13-8

Basic information

• Product Name: PERFLUORO(2-METHYL-3-PENTANONE)
• Synonyms: HEPTAFLUOROISOPROPYL PENTAFLUOROETHYL KETONE;PERFLUORO(2-METHYL-3-PENTANONE);1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl)-3-Pentanone;Perfluoro(2-methyl-3-pentanone)98%;3-Pentone,1,1,1,2,2,4,5,5,5,-nonafluoro-4-(trifluoromethyl)-;1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoroMethyl)pentan-3-one;Heptafluoroisopropyl pentafluoroethyl ketone, 1,1,1,2,2,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pentan-3-one;Perfluoro(2-methylpentan-3-one) 98%
• CAS NO: 756-13-8
• Molecular Formula: C₆F₁₂O
• Molecular Weight: 316.04
• EINECS: 436-710-6
• Mol File: 756-13-8.mol
• Article Data: 17

Chemical Properties

• Melting Point: -108°C
• Boiling Point: 49°C
• Flash Point: 9.1°C
• Appearance: /
• Density: 1,6 g/cm3
• Vapor Pressure: 196mmHg at 25°C
• Refractive Index: 1.264
• Water Solubility: 24-332.6mg/L at 25℃
• CAS DataBase Reference: PERFLUORO(2-METHYL-3-PENTANONE)(CAS DataBase Reference)
• NIST Chemistry Reference: PERFLUORO(2-METHYL-3-PENTANONE)(756-13-8)
• EPA Substance Registry System: PERFLUORO(2-METHYL-3-PENTANONE)(756-13-8)

Safety Data

• Hazard Codes: Xi
• TSCA: T
• HazardClass: IRRITANT
• Hazardous Substances Data: 756-13-8(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to almost transparent liquid

Uses

Perfluoro(2-methyl-3-pentanone) has outstanding flame retardant effect to prevent burning and is used in the protection of molten magnesium and fire extinguishing agents with no impact on the environment.

Preparation

158 g of perfluoro-2,3-epoxy-2-methyl pentane, 2.9 g of potassium fluoride, 6 g of sulfolane and 100 mL of diglyme are added into a 500 mL three-neck flask equipped with a reflux condensing tube and a mechanical stirring device, respectively. The temperature is raised to be 30 °C after stir starts. After 3 hours of reaction, the reaction product of Perfluoro(2-methyl-3-pentanone) is analyzed by gas chromatography.

Flammability and Explosibility

Notclassified

Industrial uses

Perfluoro(2-methyl-3-pentanone) can be used as a wet cleaning agent to clean steam reactors and their components, as well as to clean unwanted deposits accumulated in gas phase reactors and etch dielectric or metallic materials in gas phase reactors.

InChI:InChI=1/C6F12O/c7-2(4(10,11)12,5(13,14)15)1(19)3(8,9)6(16,17)18

Synthetic route

perfluoropropylene (116-15-4) + perfluoropropanoyl fluoride (422-61-7) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With iron(III) trifluoride; 18-crown-6 ether In acetonitrile at 90℃; for 10h; Autoclave;	98.2%
With activated carbon BAU-A-2 supported 20 wtpercent CsF In neat (no solvent) at 95℃; under 1875.19 Torr;
at 160℃; under 750.075 Torr; for 10h; Gas phase;

1,1,1,3,4,4,5,5,5-nonafluoro-2-trifluoromethyl-2,3-epoxypentane (788-67-0) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
In diethylene glycol at 60℃; for 2h; Temperature; Reagent/catalyst; Autoclave;	97.8%
With triethylamine In acetonitrile at 30℃; for 0.166667h; Temperature; Reagent/catalyst; Solvent; Time;	97.1%
With sodium fluoride In 1,2-dimethoxyethane at 20℃; for 9h;	94%

polytetrafluoroethylene (116-14-3) + perfluoroisobutyryl fluoride (677-84-9) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With iron(III) trifluoride; 18-crown-6 ether In acetonitrile at 90℃; for 10h; Autoclave;	96.8%
at 160℃; under 750.075 Torr; for 10h; Gas phase;

trans-2,3-epoxyperfluoro-4-methylpentane (788-50-1, 73041-04-0, 117642-62-3) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With cesium fluoride In 1,2-dimethoxyethane at 50℃; for 9h;	92%

2,3-bi(fluorosulfato)perfluoro-4-methylpentane (75677-98-4) → pentafluoropropionic acid (422-64-0) + perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With cesium fluoride In N,N-dimethyl-formamide at 20℃; for 4h;	A 76% B 16%

Hexafluoropropene oxide (428-59-1) + perfluoropropylene (116-15-4) → perfluoro(2-propoxypropionyl) fluoride (2062-98-8, 125037-08-3) + perfluoro-2-methyl-2-pentene (359-72-8) + perfluoro-2-methylpentan-3-one (756-13-8) + perfluoro-4-methylpent-1-ene (287101-12-6)

Conditions	Yield
With potassium fluoride In diethylene glycol dimethyl ether	A 9.7% B n/a C 63.5% D 18%

perfluoro-2-methylpent-2-ene (1584-03-8) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
Multi-step reaction with 2 steps 1: 93 percent / sodium hypochlorite / H2O; acetonitrile 2: 94 percent / NaF / 1,2-dimethoxy-ethane / 9 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: sodium hypochlorite; urea / acetonitrile; water / 3 h / 20 °C 2: potassium fluoride; 18-crown-6 ether / diethylene glycol dimethyl ether / 3 h / 30 °C View Scheme

trans-perfluoro-(4-methyl-2-pentene) (3709-71-5) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
Multi-step reaction with 2 steps 1: 70 percent / sodium hypochlorite / H2O; acetonitrile 2: antimony pentafluoride / 2.5 h / 250 °C View Scheme
Multi-step reaction with 2 steps 1: 70 percent / sodium hypochlorite / H2O; acetonitrile 2: 92 percent / CsF / 1,2-dimethoxy-ethane / 9 h / 50 °C View Scheme

Hexafluoropropene oxide (428-59-1) + perfluoropropylene (116-15-4) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
Stage #1: Hexafluoropropene oxide With potassium fluoride In diethylene glycol dimethyl ether for 2h; Heating; Stage #2: perfluoropropylene In diethylene glycol dimethyl ether; acetonitrile at 65 - 80℃; under 5250.53 Torr; for 2h;
at 160℃; under 750.075 Torr; for 10h; Gas phase;

Hexafluoropropene oxide (428-59-1) + perfluoropropylene (116-15-4) → perfluoropropanoyl fluoride (422-61-7) + perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With activated carbon BAU-A-2 supported 20 wtpercent CsF In neat (no solvent) at 130℃; Reagent/catalyst; Temperature;

Hexafluoropropene oxide (428-59-1) + perfluoropropylene (116-15-4) → perfluoro(2-propoxypropionyl) fluoride (2062-98-8, 125037-08-3) + perfluoropropanoyl fluoride (422-61-7) + perfluoro-2-methylpentan-3-one (756-13-8) + perfluoro-4-methylpent-1-ene (287101-12-6)

Conditions	Yield
With activated carbon BAU In neat (no solvent) at 130℃; Reagent/catalyst; Temperature;

perfluoro-4-methyl-2-pentene (2070-70-4) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
Multi-step reaction with 3 steps 1: sulfolane; cesium fluoride / diethylene glycol dimethyl ether / 0.5 h / 70 °C 2: sodium hypochlorite; urea / acetonitrile; water / 3 h / 20 °C 3: potassium fluoride; 18-crown-6 ether / diethylene glycol dimethyl ether / 3 h / 30 °C View Scheme
Multi-step reaction with 3 steps 1: benzyltriethylammonium bromide; potassium fluoride / acetonitrile / 4 h 2: sodium hypochlorite / diethylene glycol dimethyl ether / 4 h 3: Aliquat 336 / diethylene glycol dimethyl ether / 10 h View Scheme

perfluoro-2-methylpentan-3-one (756-13-8) → perfluoropropylene (116-15-4) + perfluoropropanoyl fluoride (422-61-7)

Conditions	Yield
With cesium fluoride at 250℃; for 2h; Product distribution;	A 68% B n/a

perfluoro-2-methylpentan-3-one (756-13-8) → 3-hydroperfluoro-2-methyl-3-pentanol (87383-00-4)

Conditions	Yield
Stage #1: perfluoro-2-methylpentan-3-one With polyethylsiloxane; tetrabutoxytitanium at 100℃; Stage #2: With sodium hydroxide In tetrahydrofuran Heating;	42%
With sodium tetrahydroborate In 1,4-dioxane for 1h;

Vinylidene fluoride (75-38-7) + perfluoro-2-methylpentan-3-one (756-13-8) → 1-<2-Trifluormethyl-perfluorpentyl-(3)-oxy>-1,1-difluor-2-brom-aethan (18329-56-1)

Conditions	Yield
(i) CsF, MeCN, (ii) /BRN= 1733321/, Br2; Multistep reaction;

perfluoro-2-methylpentan-3-one (756-13-8) → 1,1,1,2,3,3,3-Heptafluoropropane (431-89-0) + pentafluoropropionic acid (422-64-0)

Conditions	Yield
With sodium hydroxide In water Product distribution;	A 92 % Chromat. B 85 % Chromat.

perfluoro-2-methylpentan-3-one (756-13-8) + dimethyl sulfate (77-78-1) → 1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)-pentane (132182-92-4)

Conditions	Yield
With potassium fluoride In diethylene glycol dimethyl ether at 45℃;

pyrrolidine (123-75-1) + perfluoro-2-methylpentan-3-one (756-13-8) → N-tetramethyleneperfluoropropanamide (686720-34-3) + 1,1,1,2,3,3,3-Heptafluoropropane (431-89-0) + N-butyl pentafluoropropionamide (309-24-0)

Conditions	Yield
With freon 11

perfluoropropylene (116-15-4) + perfluoropropanoyl fluoride (422-61-7) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With iron(III) trifluoride; 18-crown-6 ether In acetonitrile at 90℃; for 10h; Autoclave;	98.2%
With activated carbon BAU-A-2 supported 20 wtpercent CsF In neat (no solvent) at 95℃; under 1875.19 Torr;
at 160℃; under 750.075 Torr; for 10h; Gas phase;

1,1,1,3,4,4,5,5,5-nonafluoro-2-trifluoromethyl-2,3-epoxypentane (788-67-0) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
In diethylene glycol at 60℃; for 2h; Temperature; Reagent/catalyst; Autoclave;	97.8%
With triethylamine In acetonitrile at 30℃; for 0.166667h; Temperature; Reagent/catalyst; Solvent; Time;	97.1%
With sodium fluoride In 1,2-dimethoxyethane at 20℃; for 9h;	94%

polytetrafluoroethylene (116-14-3) + perfluoroisobutyryl fluoride (677-84-9) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With iron(III) trifluoride; 18-crown-6 ether In acetonitrile at 90℃; for 10h; Autoclave;	96.8%
at 160℃; under 750.075 Torr; for 10h; Gas phase;

trans-2,3-epoxyperfluoro-4-methylpentane (788-50-1, 73041-04-0, 117642-62-3) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With cesium fluoride In 1,2-dimethoxyethane at 50℃; for 9h;	92%

2,3-bi(fluorosulfato)perfluoro-4-methylpentane (75677-98-4) → pentafluoropropionic acid (422-64-0) + perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With cesium fluoride In N,N-dimethyl-formamide at 20℃; for 4h;	A 76% B 16%

Hexafluoropropene oxide (428-59-1) + perfluoropropylene (116-15-4) → perfluoro(2-propoxypropionyl) fluoride (2062-98-8, 125037-08-3) + perfluoro-2-methyl-2-pentene (359-72-8) + perfluoro-2-methylpentan-3-one (756-13-8) + perfluoro-4-methylpent-1-ene (287101-12-6)

Conditions	Yield
With potassium fluoride In diethylene glycol dimethyl ether	A 9.7% B n/a C 63.5% D 18%

1,1,1,4,5,5,5-heptafluoro-3-(pentafluoroethyl)-2,4-bis(trifluoromethyl)pent-2-ene (30320-26-4) → perfluoro-2-methylpentan-3-one (756-13-8) + 2,2-bis(fluorosulfonyloxy)perfluoropropane

Conditions	Yield
With bis(fluorosulfuryl) peroxide at 80℃; for 192h;	A 61% B 49%
With bis(fluorosulfuryl) peroxide at 70 - 80℃;

1,1,1,3,4,4,5,5,5-nonafluoro-2-trifluoromethyl-2,3-epoxypentane (788-67-0) → perfluoro-2-methylpentan-3-one (756-13-8) + 2-chloroundecafluoro-2-methyl-3-pentanone (83714-48-1)

Conditions	Yield
With sodium chloride In diethylene glycol dimethyl ether for 20h; Heating;	A 35% B 55.8%

2-chloroundecafluoro-2-methyl-3-pentanone (83714-48-1) → perfluoropropylene (116-15-4) + perfluoropropanoyl fluoride (422-61-7) + perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With cesium fluoride In diethylene glycol dimethyl ether for 1h; Product distribution; Heating;	A n/a B n/a C 38%

1,1,1,3,4,4,5,5,5-nonafluoro-2-trifluoromethyl-2,3-epoxypentane (788-67-0) + urea (57-13-6) → perfluoro-2-methylpentan-3-one (756-13-8) + 1-(2,2,3,3,3-pentafluoropropionyl)-3-(2,2,2-trifluoro-1-trifluoromethylethyl)urea (1315483-13-6)

Conditions	Yield
In acetonitrile for 17h; Heating; Sealed tube;	A n/a B 25%

perfluoro(4-methyl-2-pentene) oxide (788-50-1) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With cesium fluoride In diethylene glycol dimethyl ether

perfluoro(4-methyl-2-pentene) oxide (788-50-1) → perfluoro(2,4-dimethyloxolane) (68970-43-4) + perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With antimony pentafluoride at 200℃; for 10h; Yield given. Yields of byproduct given;

2,3-bis(fluorosulfato)perfluoro-(2-methylpentane) (132182-90-2) → hexafluoroacetone hydrate (677-71-4) + pentafluoropropionic acid (422-64-0) + perfluoro-2-methylpentan-3-one (756-13-8) + 1,1,1,3,4,4,5,5,5-nonafluoro-2-trifluoromethyl-2,3-epoxypentane (788-67-0)

Conditions	Yield
With cesium fluoride In N,N-dimethyl-formamide at 10℃; for 1h; Yield given;	A n/a B n/a C 1.5 g D 0.3 g
With cesium fluoride In N,N-dimethyl-formamide at 10℃; for 1h;	A n/a B n/a C 1.5 g D 0.3 g

trans-2,3-epoxyperfluoro-4-methylpentane (788-50-1, 73041-04-0, 117642-62-3) → perfluoro(4-methyl-2-pentanone) (73041-05-1) + perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With antimony pentafluoride at 250℃; for 2.5h; Yield given. Yields of byproduct given;

2,3-epoxyperfluoro-3-isopropyl-4-methylpentane (103697-21-8) → perfluoropropylene (116-15-4) + perfluoro-2-methylpent-2-ene (1584-03-8) + 1,1,1,2,3,5,5,6,6,7,7,7-dodecafluoro-2,4-bis(trifluoromethyl)hept-3-ene (30320-29-7) + perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With cesium fluoride In diethylene glycol dimethyl ether for 2h; Heating; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;	A 0.8 g B n/a C n/a D n/a
With cesium fluoride In diethylene glycol dimethyl ether for 2h; Heating; Yield given. Further byproducts given. Title compound not separated from byproducts;	A 0.8 g B n/a C n/a D n/a

perfluoro-2-methylpent-2-ene (1584-03-8) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
Multi-step reaction with 2 steps 1: 93 percent / sodium hypochlorite / H2O; acetonitrile 2: 94 percent / NaF / 1,2-dimethoxy-ethane / 9 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: sodium hypochlorite; urea / acetonitrile; water / 3 h / 20 °C 2: potassium fluoride; 18-crown-6 ether / diethylene glycol dimethyl ether / 3 h / 30 °C View Scheme

trans-perfluoro-(4-methyl-2-pentene) (3709-71-5) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
Multi-step reaction with 2 steps 1: 70 percent / sodium hypochlorite / H2O; acetonitrile 2: antimony pentafluoride / 2.5 h / 250 °C View Scheme
Multi-step reaction with 2 steps 1: 70 percent / sodium hypochlorite / H2O; acetonitrile 2: 92 percent / CsF / 1,2-dimethoxy-ethane / 9 h / 50 °C View Scheme

Hexafluoropropene oxide (428-59-1) + perfluoropropylene (116-15-4) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
Stage #1: Hexafluoropropene oxide With potassium fluoride In diethylene glycol dimethyl ether for 2h; Heating; Stage #2: perfluoropropylene In diethylene glycol dimethyl ether; acetonitrile at 65 - 80℃; under 5250.53 Torr; for 2h;
at 160℃; under 750.075 Torr; for 10h; Gas phase;

Hexafluoropropene oxide (428-59-1) + perfluoropropylene (116-15-4) → perfluoropropanoyl fluoride (422-61-7) + perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
With activated carbon BAU-A-2 supported 20 wtpercent CsF In neat (no solvent) at 130℃; Reagent/catalyst; Temperature;

Hexafluoropropene oxide (428-59-1) + perfluoropropylene (116-15-4) → perfluoro(2-propoxypropionyl) fluoride (2062-98-8, 125037-08-3) + perfluoropropanoyl fluoride (422-61-7) + perfluoro-2-methylpentan-3-one (756-13-8) + perfluoro-4-methylpent-1-ene (287101-12-6)

Conditions	Yield
With activated carbon BAU In neat (no solvent) at 130℃; Reagent/catalyst; Temperature;

perfluoro-4-methyl-2-pentene (2070-70-4) → perfluoro-2-methylpentan-3-one (756-13-8)

Conditions	Yield
Multi-step reaction with 3 steps 1: sulfolane; cesium fluoride / diethylene glycol dimethyl ether / 0.5 h / 70 °C 2: sodium hypochlorite; urea / acetonitrile; water / 3 h / 20 °C 3: potassium fluoride; 18-crown-6 ether / diethylene glycol dimethyl ether / 3 h / 30 °C View Scheme
Multi-step reaction with 3 steps 1: benzyltriethylammonium bromide; potassium fluoride / acetonitrile / 4 h 2: sodium hypochlorite / diethylene glycol dimethyl ether / 4 h 3: Aliquat 336 / diethylene glycol dimethyl ether / 10 h View Scheme

perfluoro-2-methylpentan-3-one (756-13-8) → perfluoropropylene (116-15-4) + perfluoropropanoyl fluoride (422-61-7)

Conditions	Yield
With cesium fluoride at 250℃; for 2h; Product distribution;	A 68% B n/a

perfluoro-2-methylpentan-3-one (756-13-8) → 1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl)pentanol (87383-00-4)

Conditions	Yield
Stage #1: perfluoro-2-methylpentan-3-one With polyethylsiloxane; tetrabutoxytitanium at 100℃; Stage #2: With sodium hydroxide In tetrahydrofuran Heating;	42%
With sodium tetrahydroborate In 1,4-dioxane for 1h;
With sodium tetrahydroborate at 0℃; for 1.5h;

Vinylidene fluoride (75-38-7) + perfluoro-2-methylpentan-3-one (756-13-8) → 1-<2-Trifluormethyl-perfluorpentyl-(3)-oxy>-1,1-difluor-2-brom-aethan (18329-56-1)

Conditions	Yield
(i) CsF, MeCN, (ii) /BRN= 1733321/, Br2; Multistep reaction;

perfluoro-2-methylpentan-3-one (756-13-8) → 1,1,1,2,3,3,3-Heptafluoropropane (431-89-0) + pentafluoropropionic acid (422-64-0)

Conditions	Yield
With sodium hydroxide In water Product distribution;	A 92 % Chromat. B 85 % Chromat.

perfluoro-2-methylpentan-3-one (756-13-8) + dimethyl sulfate (77-78-1) → 1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)-pentane (132182-92-4)

Conditions	Yield
With potassium fluoride In diethylene glycol dimethyl ether at 45℃;

pyrrolidine (123-75-1) + perfluoro-2-methylpentan-3-one (756-13-8) → N-tetramethyleneperfluoropropanamide (686720-34-3) + 1,1,1,2,3,3,3-Heptafluoropropane (431-89-0) + N-butyl pentafluoropropionamide (309-24-0)

Conditions	Yield
With freon 11

perfluoro-2-methylpentan-3-one (756-13-8) + diethylamine (109-89-7) → C9H12F5NO (21016-40-0) + 1,1,1,2,3,3,3-Heptafluoropropane (431-89-0) + N-Diethyl-pentafluor-propionsaeureamid (10186-77-3) + ethylamine pentafluoropropionate

Conditions	Yield
With freon 11

perfluoro-2-methylpentan-3-one (756-13-8) + N-butylamine (109-73-9) → 1,1,1,2,3,3,3-Heptafluoropropane (431-89-0) + (butylidene)butylamine (4853-56-9) + N-butyl pentafluoropropionamide (309-24-0)

Conditions	Yield
With freon 11

perfluoro-2-methylpentan-3-one (756-13-8) → pentafluoropropionic acid (422-64-0)

Conditions	Yield
With water pH=8 - 14;

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 677-84-9 perfluoroisobutyryl fluoride 
• 2070-70-4 perfluoro-4-methyl-2-pentene 
• 428-59-1 Hexafluoropropene oxide 
• 116-15-4 perfluoropropylene 
• 422-61-7 perfluoropropanoyl fluoride 
• 788-67-0 1,1,1,3,4,4,5,5,5-nonafluoro-2-trifluoromethyl-2,3-epoxypentane 
• 57-13-6 urea 
• 3709-71-5 trans-perfluoro-(4-methyl-2-pentene) 
• 1584-03-8 perfluoro-2-methylpent-2-ene 
• 83714-48-1 2-chloroundecafluoro-2-methyl-3-pentanone 
• 103697-21-8 2,3-epoxyperfluoro-3-isopropyl-4-methylpentane 
• 788-50-1 trans-2,3-epoxyperfluoro-4-methylpentane 
• 75677-98-4 2,3-bi(fluorosulfato)perfluoro-4-methylpentane 

Downstream Products

• 132182-92-4 1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)-pentane 
• 686720-34-3 N-tetramethyleneperfluoropropanamide 
• 431-89-0 1,1,1,2,3,3,3-Heptafluoropropane 
• 309-24-0 N-butyl pentafluoropropionamide 
• 21016-40-0 C₉H₁₂F₅NO 
• 10186-77-3 N-Diethyl-pentafluor-propionsaeureamid 
• 4853-56-9 (butylidene)butylamine 
• 422-64-0 pentafluoropropionic acid 
• 116-15-4 perfluoropropylene 
• 422-61-7 perfluoropropanoyl fluoride 

Relevant articles and documents

Method for synthesizing perfluoro(2-methyl-3-pentanone)

The invention discloses a method for synthesizing perfluoro(2-methyl-3-pentanone). The method comprises the following steps: in the presence of a polar aprotic solvent, carrying out an isomerization synthesis reaction in a micro-channel reactor by taking perfluoro-2,3-epoxy-2-methylpentane as a raw material and using an organic amine or metal fluoride as a catalyst to obtain a reaction product, and sequentially carrying out standing separation and rectification treatment on the reaction product to obtain perfluoro(2-methyl-3-pentanone). According to the invention, a reaction is performed by using a micro-channel reactor, so that the whole isomerization synthesis reaction cannot contact water or water vapor so as to avoid the generation of by-products and improve the conversion rate and theyield of the perfluoro(2-methyl-3-pentanone); and raw materials and a catalyst are subjected to high-speed uniform mixing and heat and mass transfer in the micro-channel reactor, so that the rate ofthe synthesis reaction is increased, the continuous and efficient synthesis of perfluoro(2-methyl-3-pentanone) is realized, and the method is good in repeatability, rapid in system response, easy forautomatic control and amplified production, almost free of amplification effect, high in safety, less in three wastes and easy for industrial production.

Method for preparing pentafluoride ethyl perfluoro isopropyl ketone through gas phases

The invention discloses a method for preparing pentafluoride ethyl perfluoro isopropyl ketone through gas phases. The method is characterized in that under the existence of addition catalysts, hexafluoropropylene and hexafluoropropylene oxide or pentafluoropropionyl fluoride take gas phase addition reaction to obtain the pentafluoride ethyl perfluoro isopropyl ketone, or tetrafluoroethylene and heptafluorobutyl fluoride take gas phase addition reaction to obtain the pentafluoride ethyl perfluoro isopropyl ketone. The method has the advantages that the reaction route is short; in addition, rawmaterials such as the hexafluoropropylene, the tetrafluoroethylene, the hexafluoropropylene oxide and carbonyl fluoride can be easily obtained; the cost is low; the yield of the pentafluoride ethyl perfluoro isopropyl ketone is high; the continuous large-scale industrial production can be realized through the route.

Preparation method of C6-fluoroketone

The invention discloses a preparation method of C6-fluoroketone. C6-fluoroketone is called perfluoro-2-methyl-3-pentanone. The method includes the steps that in the presence of an organic guanidine catalyst and a solvent, perfluoro-2,3-epoxy-2-methylpentane reacts for 1-5 hours at the temperature of 0-80 DEG C; the organic guanidine catalyst is selected from one of or a mixture of two or more of metformin, bicyclic guanidine, chlorination bicyclic guanidine, tetramethyl guanidine and conjugated tetramethyl guanidine and other guanidyl compounds. The mole yield of the product obtained through the method is larger than 95%, reaction selectivity is high, reaction conditions are mild, and the preparation method is environmentally friendly.