7688-25-7Relevant articles and documents
Catalytic Cleavage of Unactivated C(aryl)-P Bonds by Chromium
Ling, Liang,Luo, Meiming,Tang, Jinghua,Yuan, Shuqing,Zeng, Xiaoming
, p. 1581 - 1586 (2022/03/14)
We describe here the coupling to transform aryl phosphine derivatives by the cleavage of unactivated C(aryl)-P bonds with chromium catalysis, allowing us to achieve the reaction with alkyl bromides and arylmagnesium reagents under mild conditions. Mechani
Method for preparing aryl ketone derivatives
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Paragraph 0019, (2019/10/01)
The present invention discloses a method for preparing aryl ketone derivatives. The method provided by the invention adopts 1-(hetero)arylcycloalcohol as a starting material, and raw materials are easy to obtain and have a plurality of kinds; the products obtained by utilizing the method have various types and wide applications, and the obtained products can be conveniently converted and derivatized to obtain important phosphorus ligands and catalysts; and in addition, the method disclosed in the invention has the advantages of mild reaction conditions, a high yield of the target products, lowpollution and a simple reaction operation and post-treatment process, and is suitable for industrial production.
Bisphosphine catalyzed sequential [3 + 2] cycloaddition and Michael addition of ynones with benzylidenepyrazolones: Via dual α′,α′-C(sp3)-H bifunctionalization to construct cyclopentanone-fused spiro-pyrazolones
Zhang, Jiayong,Miao, Zhiwei
supporting information, p. 9461 - 9471 (2019/01/03)
A bisphosphine-catalyzed sequential [3 + 2] cycloaddition and Michael addition reaction of ynones with benzylidenepyrazolones has been developed. Under the catalysis of DPPB [1,4-bis(diphenylphosphino)butane], the reaction proceeded smoothly to give spiro-[cyclopentanone] pyrazolone derivatives in moderate to good yields with good diastereoselectivities via sequential dual α′,α′-C(sp3)-H bifunctionalization annulation. This strategy provides a novel route toward the synthesis of spiro-[cyclopentanone] pyrazolones containing three contiguous stereocenters which possess potential pharmaceutical activities.
Synthesis of pincer ruthenium RuCl(CNN)(PP) catalysts from [RuCl(μ-Cl)(η6-p-cymene)]2
Zhang, Shuanming,Baratta, Walter
supporting information, p. 3339 - 3342 (2013/07/19)
The cationic [RuCl(η6-p-cymene)(HCNNa)]Cl (1a) (HCNNa = 1-(6-arylpyridin-2-yl)methanamine) and the neutral RuCl 2(η6-p-cymene)(HCNNb) (1b) (HCNN b = 2-aminomethylbenzo[h]quinoline) complexes have been obtained by reaction of the precursor [RuCl(μ-Cl)(η6-p-cymene)] 2 with the corresponding nitrogen ligand (HCNNa and HCNNb) in THF. Complex 1a reacts cleanly with monodentate (P = PPh3) and bidentate phosphines (PP = dppb, dppf) in ethanol in the presence of NEt3, affording the pincer catalysts RuCl(CNN a)(PPh3)2 (2) and RuCl(CNNa)(PP) (PP = dppb 3, dppf 4). Similarly, the benzo[h]quinoline pincer derivative RuCl(CNNb)(dppb) (5) is obtained from 1b and dppb. Complex 3 has also been prepared in a one-pot reaction from [RuCl(μ-Cl)(η6-p- cymene)]2, HCNNa, and dppb in ethanol. Similarly, the chiral complex RuCl(CNNa)((R,S)-Josiphos) was isolated as a single stereoisomer by treatment of [RuCl(μ-Cl)(η6-p-cymene)] 2 with HCNNa and (R,S)-Josiphos in 1-butanol. Reaction of 1a and 1b with dppb affords cymene diphosphine species by displacement of the HCCN ligand.
A catalytic method for the reduction of secondary and tertiary phosphine oxides
Berthod, Mika?l,Favre-Réguillon, Alain,Mohamad, Jahjah,Mignani, Gérard,Docherty, Gordon,Lemaire, Marc
, p. 1545 - 1548 (2008/02/05)
TMDS has been found to be an efficient hydride source for the reduction of tertiary and secondary phosphine oxides using a catalytic amount of Ti(Oi-Pr)4. All classes of tertiary phosphine oxides, such as triaryl, trialkyl, and diphosphine, were effectively reduced. Georg Thieme Verlag Stuttgart.
A mild and efficient CsOH-promoted synthesis of ditertiary phosphines
Honaker, Matthew T.,Salvatore, Ralph Nicholas
, p. 277 - 283 (2007/10/03)
A mild and efficient method for the synthesis of ditertiary phosphines has been developed. In the presence of cesium hydroxide, molecular sieves, and DMF, various dihalides were coupled with diphenylphosphine at room temperature, and the results have demonstrated that this methodology offers a general synthetic procedure producing a variety of ditertiary phosphines in high yields.
CsOH-promoted P-alkylation: A convenient and highly efficient synthesis of tertiary phosphines
Honaker, Matthew T.,Sandefur, Benjamin J.,Hargett, James L.,McDaniel, Alicia L.,Salvatore, Ralph Nicholas
, p. 8373 - 7377 (2007/10/03)
A mild and efficient method for the synthesis of tertiary phosphines and ditertiary phosphines has been developed. In the presence of cesium hydroxide, molecular sieves and DMF at room temperature, various secondary phosphines and alkyl bromides were examined, and the results have demonstrated that this methodology offers a general synthetic procedure to produce tertiary phosphines in moderate to high yields. Optically active tertiary phosphine synthesis is also described.
Preparation of organohalosilanes
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, (2008/06/13)
When oganohalosilanes are prepared by charging a reactor with a contact mass containing a metallic silicon powder and a copper catalyst, and introducing an organohalide-containing gas into the reactor to effect the direct reaction, a poly(organo)phosphino compound is added to the contact mass. The invention is successful in producing organohalosilanes at a significantly improved production rate without reducing the selectivity of useful silane.
Method for producing benzoic acid derivatives
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, (2008/06/13)
The invention relates to a method for producing a benzoic acid derivative represented by the general formula (1). The method includes the step of reacting an aromatic compound represented by the general formula (2), with carbon monoxide and a hydroxy compound (i.e., water or an alcohol), in the presence of (a) a metal compound containing a metal of 8, 9 and 10 groups of periodic table, (b) a first phosphine derivative represented by the general formula (R1)2P—Q—P(R1)2, and (c) a base, It is possible to easily and efficiently produce the benzoic acid derivative by the method.
Process for the hydrogenation of imines
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, (2008/06/13)
A process for the hydrogenation of imines with hydrogen under elevated pressure in the presence of iridium catalysts containing diphosphine ligands, with or without an inert solvent, the reaction mixture containing a soluble ammonium chloride, bromide or iodide or a soluble metal chloride, bromide, or iodide, wherein the reaction mixture additionally contains at least one solid acid with the exception of ion exchangers. Improved optical yields and high chemical conversion rates are achieved while the catalyst is easily separable.
