97-97-2

Basic information

• Product Name: Chloroacetaldehyde dimethyl acetal
• Synonyms: 2-Chlor-1,1-dimethoxyethan;CHLORACETALDEHYDDIMETHYLACETAL;2-Chloro-1,1-dimethoxyethane, Dimethyl chloroacetal;2-Chloro-1,1-dimethoxyethane, CADMA, Dimethyl chloroacetal;2,2-Dimethoxyethyl chloride;Chloroacetaldehyde dimethyl acetal,97%;Chloroacetaldehyde d;Chloroacetaldehyde diMethyl acetal, 97% 250ML
• CAS NO: 97-97-2
• Molecular Formula: C₄H₉ClO₂
• Molecular Weight: 124.57
• EINECS: 202-624-0
• Product Categories: Pyridines ,Halogenated Heterocycles;Pharmaceutical Intermediates
• Mol File: 97-97-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: -73 °C
• Boiling Point: 128-130 °C(lit.)
• Flash Point: 84 °F
• Appearance: Clear colorless to yellow/Liquid
• Density: 1.094 g/mL at 25 °C(lit.)
• Vapor Pressure: 13.494mmHg at 25°C
• Refractive Index: n20/D 1.415(lit.)
• Storage Temp.: Flammables area
• Solubility: 52g/l
• Explosive Limit: 2.3%(V)
• Water Solubility: 52 g/L (20 ºC)
• Sensitive: Moisture Sensitive
• BRN: 1733700
• CAS DataBase Reference: Chloroacetaldehyde dimethyl acetal(CAS DataBase Reference)
• NIST Chemistry Reference: Chloroacetaldehyde dimethyl acetal(97-97-2)
• EPA Substance Registry System: Chloroacetaldehyde dimethyl acetal(97-97-2)

Safety Data

• Hazard Codes: Xn,F
• Statements: 10-22-52/53-20/21/22-40-36/37/38
• Safety Statements: 28A-26-16-36-23
• RIDADR: UN 1989 3/PG 3
• WGK Germany: 2
• F: 1
• TSCA: Yes
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 97-97-2(Hazardous Substances Data)

Usage

Uses

Chloroacetaldehyde dimethyl acetal can be used as a reactant to synthesize:2-(chloromethyl)-4,7-dethyl-1,3-dioxepane2-(chloromethyl)-5,6-benzo-1,3-dioxepane ketene dimethyl acetal

General Description

Chloroacetaldehyde dimethyl acetal is a clear, colorless liquid. It reacts with hydroxythiol to form hydroxy acetal.

Purification Methods

Purify the acetal by fractional distillation. [Melhotra J Indian Chem Soc 36 4405 1959, Beilstein 1 IV 3134.]

InChI:InChI=1/C4H9ClO2/c1-6-4(3-5)7-2/h4H,3H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 108-05-4 vinyl acetate 
• 2280-44-6 D-Glucose 
• 10257-28-0 D-Galactose 
• 75-07-0 acetaldehyde 
• 75-01-4 chloroethylene 
• 107-20-0 2-chloroethanal 
• 95684-29-0 2-chloro-1-hydroxyethyl 2-chloro-1-methoxyethyl peroxide 
• 123-63-7 paracetaldehyde 
• 107-25-5 methoxyethene 
• 124-41-4 sodium methylate 
• 41683-62-9 1,2-dichloro-1-methoxy-ethane 

Downstream Products

• 22633-57-4 4-(2,2-dimethoxyethyl)morpholine 
• 53484-82-5 2-methoxy-[1,4]oxathiane 
• 6538-93-8 5,6-dihydro-1,4-oxathiine 
• 2568-30-1 2-chloromethyl-1,3-dioxolane 
• 98544-93-5 butyl-(2,2-dimethoxy-ethyl)-amine 
• 54879-88-8 N-benzyl-2,2-dimethoxyethylamine 
• 62810-43-9 1-bromo-3-(2,2-dimethoxyethoxy)benzene 
• 25347-49-3 1,2-bis(p-ethylphenyl)ethylene 
• 64533-19-3 1-Chloro-4-(2-chloro-1-methoxy-ethanesulfonyl)-benzene 
• 922-69-0 1,1-dimethoxyethylene 
• 18889-01-5 1,1-Bis-phenylmercapto-aethylen 
• 17053-13-3 2.2-Dimethoxy-aethylphosphonsaeure-diaethylester 
• 13169-01-2 1-methoxypropyne 
• 3461-34-5 methyl 3,3-diphenylacrylate 

Relevant articles and documents

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Green method for preparing chloroacetaldehyde dialkyl alcohol from vinyl acetate

The invention discloses a green process for preparing chloroacetaldehyde dimethyl acetal from vinyl acetate, which comprises the following steps: directly chlorinating vinyl acetate in the presence ofa polymerization inhibitor and a polarity induction reagent to obtain (1,2-dichloroethyl) acetate, adding (1,2-dichloroethyl) acetate into methanol, carrying out methanolysis, neutralizing with ammonia water, and carrying out post-treatment to obtain chloroacetaldehyde dimethyl acetal. A free radical polymerization inhibitor needs to be added before chlorination of vinyl acetate to prevent free radical polymerization in the chlorination process, and quaternary ammonium salt or quaternary phosphonium salt is used as a polarity induction reagent to promote electrophilic addition reaction of chlorine to vinyl acetate. According to the method, expensive raw materials and reagents are not used, operation is easy and convenient, the yield is high, the byproduct ammonium chloride is convenient to recycle, benefits are good, and industrialization is easy to achieve.

Green process technology for preparing chloroacetaldehyde dimethyl acetal from vinyl chloride

The invention discloses a green process technology for preparing chloroacetaldehyde dimethyl acetal from vinyl chloride. The process comprises the following steps: carrying out electrophilic additionreaction and nucleophilic substitution reaction in a tower-type reactor by using chloroethylene, absolute methanol and chlorine as raw materials; sodium methoxide is used as an acid-binding agent, hydrogen chloride generated in the reaction process is neutralized in time, sodium chloride with low solubility is generated and gradually gathered to the bottom of a tower, the concentration of chlorineanions in a reaction system is greatly reduced, and generation of a byproduct 1, 1, 2-trichloroethane is avoided. The method is convenient to control, high in yield, few in side reaction, single in product, convenient to separate and purify, green and pollution-free; and the solvent methanol can be recovered by directly adopting rectification, and the recovered methanol can be repeatedly used.