Pellizzari Reaction

G. Pellizzari, Gazz. Chim. Ital. 41, II, 20 (1911).

Formation of substituted 1,2,4-triazoles by the condensation of amides and acyl hydrazines. When the acyl groups of the amide and the acylhydrazine are different, interchange of acyl groups may occur with formation of a mixture of triazoles:



M. R. Atkinson, J. B. Polya, J. Chem. Soc. 1952, 3418; P. Karrer, Organic Chemistry (New York, 4th ed., 1950) p 802; C. W. Bird, C. K. Wong, Tetrahedron Letters 1974, 1251. Cf. Einhorn-Brunner Reaction.