- Nicergoline
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is a kind of API. There are some basic informations about this crude drug:
(1)CAS No.: ;
(2)MF: C24H26BrN3O3;
(3)EINECS No.: 248-694-6;
(4)Other Names: 1-Methyl-lumilysergol 8-(5-bromonicotinate) 10-methyl ether.Nicergoline is an ergoloid mesylate derivative used to treat senile dementia and other disorders with vascular origins. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy.
Nicerogline is used in the following cases:
Acute and chronic cerebral metabolic-vascular disorders (cerebral arteriosclerosis, thrombosis and cerebral embolism, transitory cerebral ischaemia). Acute and chronic peripheral metabolic-vascular disorders (organic and functional arteriopathies of the limbs), Raynaud’s disease and other syndromes caused by altered peripheral irrigation.
Coadjutant therapy in clinical situations accompanied by platelet hyper-aggregability, arterial tension.
Corio-retinal vascular disorders: , diabetic retinopathy, macular degeneration and retinal angiosclerosis
Oto-vestibular problems of a vascular nature: dizziness, auditory hallucinations, hypoacusis.
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