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 Blanc Reaction
  • Blanc Reaction
  • Blanc Reaction (Chloromethylation)

    G. Blanc, Bull. Soc. Chim. France [4], 33, 313 (1923).

    Introduction of the chloromethyl group into aromatic rings on treatment with formaldehyde and hydrogen chloride in the presence of zinc chloride:



    Reviews: R. C. Fuson, C. H. McKeever, Org. React. 1, 63 (1942); G. Olah, W. S. Tolgyesi, in Friedel-Crafts and Related Reactions vol. II, Part 2, G. Olah, Ed. (Interscience, New York, 1963) pp 659-784. Cf. Quelet Reaction.


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