Fenton Reaction

H. J. H. Fenton, Proc. Chem. Soc. 9, 113 (1893); J. Chem. Soc. 65, 899 (1894).

Oxidation of α-hydroxy acids with hydrogen peroxide and ferrous salts (Fenton's reagent) to α-keto acids or of 1,2-glycols to hydroxy aldehydes:



W. A. s in Organic Chemistry vol. 4, H. Gilman, Ed. (Wiley, New York, 1953) p 1157; G. Sosnovsky, D. Rawlinson in Organic Peroxides vol. 2, D. Swern, Ed. (Interscience, New York, 1970) pp 269-336; C. Walling, Accts. Chem. Res. 8, 125 (1975); T. Tezuka et al., J. Am. Chem. Soc. 103, 3045 (1981); C. Walling, K. Amarnath, ibid. 104, 1185 (1982). Extension to additional substrates: aromatic alcohols: F. J. Benitez et al., Ind. Eng. Chem. Res. 38, 1341 (1999); L. Lunar et al., Water Res. 34, 1791 (2000); N-heterocyclics: M. A. Oturan et al., New J. Chem. 23, 793 (1999); E. L. Bier et al., Environ. Toxicol. Chem. 18, 1078 (1999); organometals: K. Banerjee et al., Environ. Prog. 18, 280 (1999).