Guerbet Reaction

M. Guerbet, Compt. Rend. 128, 511 (1899).

Condensation of 1° or 2° alcohols at high temperature and pressure in the presence of alkali metal hydroxide or alkoxide by a dehydrogenation, aldol condensation, q.v., and hydrogenation sequence:



H. Machemer, Angew. Chem. 64, 213 (1952); S. Veibel, J. T. Nielsen, Tetrahedron 23, 1723 (1967); G. Gregorio et al., J. Organometal. Chem. 37, 385 (1972); E. Klein, et al., Ann. 1973, 1004. -promoted reaction: P. L. Burk et al., J. Mol. Catal. 33, 1 (1985).