Kuhn-Winterstein Reaction

R. Kuhn, A. Winterstein, Helv. Chim. Acta 11, 87 (1928).

Conversion of 1,2-glycols into trans olefins by reaction with diphosphotetraiodide (P₂I₄) or other halogenated reagents. This reaction is useful in the preparation of polyenes:



Kuhn et al., Ber. 71, 1510 (1938); 84, 566 (1961); 88, 309 (1965); Inhoffen et al., Ann. 684, 24 (1965); H. Kessler, W. Ott, Tetrahedron Letters 1974, 1383; W. W. Win et al., J. Org. Chem. 59, 2803 (1994).