McFadyen-Stevens Reaction

J. S. McFadyen, T. S. Stevens, J. Chem. Soc. 1936, 584.

Base-catalyzed thermal decomposition of acylbenzenesulfonylhydrazines to aldehydes:



E. Mosettig, Org. React. 8, 232-240 (1954); S. Siddappa, G. A. Bhat, J. Chem. Soc. C 1971, 178; S. B. Matin et al., J. Org. Chem. 39, 2285 (1974); M. Nair, H. Shechter, Chem. Commun. 1978, 793. Alternative hydrazide reagent: C. C. Dudman et al., Tetrahedron Letters 1980, 4645. Synthetic applications: H. Graboyes et al., J. Heterocyclic Chem. 12, 1225 (1975); R. K. Manna et al., Synth. Commun. 28, 9 (1998).