Trost Desymmetrization

B. M. Trost et al., J. Am. Chem. Soc. 114, 9333 (1992).

Formation of an enantiomerically pure, azide or amine containing, five or six membered ring by a pallidium catalyzed desymmetrization using a nitrogen nucleophile, where the palladium complex is derived from a chiral ligand and π-allylpalladium chloride:



S. R. Pulley, B. M. Trost, J. Am. Chem. Soc. 117, 10143 (1995).