Williamson Synthesis

A. W. Williamson, J. Chem. Soc. 4, 229 (1852).

Synthesis of ethers by alkylation of alkoxides with alkyl halides or alkyl sulfates:



Reviews: O. C. Dermer, Chem. Rev. 14, 409 (1934); H. Feuer, J. Hooz in The Chemistry of the Ether Linkage, S. Patai, Ed. (Wiley, New York, 1967) pp 446-460; H. O. Kalinowski et al., Ber. 114, 477 (1981); J. March, Advanced Organic Chemistry (Wiley-Interscience, New York, 4th ed., 1992) p 386.