DRAGON is a well-known software for the calculation of more than 1600 molecular descriptors from several input formats (MDL, SYBYL, HyperChem, Smiles). 

dragonX for Linux systems (version 1.2): The DRAGON version for Linux system (dragonX) is available working with an unlimited number of molecules with relevant time performances.

DRAGON for Windows systems (version 5.4): The new release 5.4 of DRAGON for Windows has been deeply revised. In particular: the maximum number of molecules per batch has been increased from 10,000 to 50,000; the maximum number of atoms per molecule has been increased from 300 to 1,000; MlogP and AlogP have been further improved; charged molecules are now correctly dealt with reading of SMILES molecules has been greatly extended; some errors have been fixed; molecules containing Ge, Sb, Bi atoms are now processed for a total of 38 atoms.