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 Production Method of Salmeterol
  • Production Method of Salmeterol
  • (CAS NO.: ), with other name of , 4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-, (+-)-, could be produced through many synthetic methods.

    Following is one of the synthesis routes:
    (I) could react with 1,6-di in the presence of NaH in THF to produce the ether derivative (III), which is then condensed with 5-(2-amino-1-hydroxyethyl)-2-hydroxybenzyl alcohol (IV) by means of KI and triethylamine in hot DMF.

    Production Method of Salmeterol


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