- Synthesis of Ranolazine
-
(CAS NO.: ), with its systematic name of , N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-, could be produced through many synthetic methods.
Following is one of the synthesis routes:
The acylation of 2,6-dimethylaniline (II) with chloroacetyl chloride in the presence of triethylamine in dichloromethane affords N-(2,6-dimethylphenyl) chloroacetamide (III), which is condensed with piperidine (IV) in refluxing ethanol to yield N-(2,6-dimethylphenyl)-2-piperazinoacetamide IV). At last, this compound is condensed with 3-(2-methoxyphenoxy)-12-epoxypropane (VI) in refluxing methanol toluene.
Prev:No record
Next:No record - 【Back】【Close 】【Print】【Add to favorite 】
-
Health and Chemical more >
-
Hot Products
- 68152-70-5 Rosin, polymer with bisphenol A, formaldehyde and glycerol
- 1214-39-7 1H-Purin-6-amine, N- (phenylmethyl)-
- 906673-24-3 5-(4-cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole
- 51147-75-2 sodium bis[2-(3-chlorophenyl)-2,4-dihydro-4-[[2-hydroxy-5-mesylphenyl]azo]-5-methyl-3H-pyrazol-3-onato(2-)]chromate(1-)
- 51066-74-1 dimethylammonium iodide
- 10094-62-9 A-D-GLUCOHEPTONIC ACID SODIUM
- 3251-23-8 Copper dinitrate
- 852246-52-7 Benzeneacetonitrile, 2-methyl-α-[2-[[[(4-methylphenyl)sulfonyl]oxy]imino]-3(2H)-thienylidene]-
- 148-24-3 8-Hydroxyquinoline
- 1344-37-2 Pigment Yellow 34
- 15502-80-4 2-Methyl-4,6-quinolinediol
- 219756-63-5 α-Sulfo-ω-(undecyloxy)poly(oxy-1,2-ethanediyl), sodium salt, branched and linear


