n-Dodecyl bromide (CAS NO.: ), with other names like , 1-bromo-, could be produced through the following synthetic methods.

In a 500-cc. distilling flask, fitted with a thermometer and an inlet tube leading to the bottom, is placed 186 g. (1 mole) of n-dodecyl alcohol. An adapter, one end of which is immersed in about 75 cc. of water contained in a 125-cc. Erlenmeyer flask, is attached to the side arm of the flask. All connections are of rubber. The alcohol is heated to 100°, and dry hydrogen bromide is passed in at 100–120°until no more absorption occurs. The crude bromide, together with any of the product that has been carried over into the receiving flask, is transferred to a separatory funnel, separated from the aqueous hydrobromic acid formed during the reaction, and shaken with one-third its volume of concentrated sulfuric acid. The lower acid layer is drawn off and discarded. The residual bromide is mixed with an equal volume of 50 per cent methyl alcohol, and aqueous ammonia is added with intermittent shaking until the solution is alkaline to phenolphthalein. The lower bromide layer is drawn off and washed once with an equal volume of 50 per cent methyl alcohol. It is then dried with calcium chloride, filtered, and distilled. The yield of product boiling at 199.5–201.5°/100 mm. or 134–135°/6 mm. is 220 g. (88 per cent of the theoretical amount).