- One Synthetic Way of Miriplatin
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Miriplatin (CAS NO.: ), with other name of (SP-4-2)-((1R,2R)--1,2-diamine-N,N')bis(tetradecanoato-O)platinum, could be produced through many synthetic methods.
Following is one of the synthesis routes:
Dichlorocyclohexane-1,2-diamine platinum complex (II) was prepared from (R,R)-1,2-cyclohexanediamine (I) according to a known method. Subsequent treatment of (II) with aqueous silver nitrate produced the diaqua complex (III). Finally, displacement of H2O by means of sodium myristate (IV) gave rise to the title compound.
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