NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1974),p. 245.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

The Ethyl methanesulfonate with CAS registry number of 62-50-0 is also known as Methanesulphonic acid ethyl ester. The IUPAC name and product name are the same. Its EINECS registry number is 200-536-7. In addition, the formula is C₃H₈O₃S and the molecular weight is 124.15. This chemical is a clear colorless oily liquid that at low levels cause damage to health. It is soluble in ether, ethanol, chloroform, slightly soluble in water and should be sealed in cool, dry place. What's more, this chemical can be used as bacteria mutagen and also is used for organic synthesis and cancer research.

Physical properties about Ethyl methanesulfonate are: (1)ACD/LogP: -0.03; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.03; (4)ACD/LogD (pH 7.4): -0.03; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 22.82; (8)ACD/KOC (pH 7.4): 22.82; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.416; (13)Molar Refractivity: 26.48 cm³; (14)Molar Volume: 105.4 cm³; (15)Surface Tension: 33.8 dyne/cm; (16)Density: 1.177 g/cm³; (17)Flash Point: 83.5 °C; (18)Enthalpy of Vaporization: 43.24 kJ/mol; (19)Boiling Point: 214.4 °C at 760 mmHg; (20)Vapour Pressure: 0.228 mmHg at 25 °C.

Preparation of Ethyl methanesulfonate: it is prepared by reaction of 1,1,1-triethoxy-ethane with methanesulfonic acid. The reaction needs solvent CH₂Cl₂ with other condition of ambient temperature for 30 minutes. The yield is about 92%.

Uses of Ethyl methanesulfonate: it is used to produce 4-bromo-1-ethylpiperidine by reaction with 4-bromo-piperidine. The reaction occurs with reagent Et₃N and solvent benzene with other condition of heating for 48 hours. The yield is about 61%.

When you are using this chemical, please be cautious about it. As a chemical, it is harmful if swallowed and may cause heritable genetic damage. However, there is limited evidence of a carcinogenic effect. During using it, wear suitable protective clothing, gloves and eye/face protection. Do not breathe gas/fumes/vapour/spray and obtain special instructions before use. In case of accident or if you feel unwell seek medical advice immediately

You can still convert the following datas into molecular structure:
1. Canonical SMILES: CCOS(=O)(=O)C
2. InChI: InChI=1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3
3. InChIKey: PLUBXMRUUVWRLT-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	435mg/kg (435mg/kg)		Chemico-Biological Interactions. Vol. 3, Pg. 117, 1971.
mouse	LD50	oral	470mg/kg (470mg/kg)		Mutation Research. Vol. 223, Pg. 373, 1989.
rat	LD50	intraperitoneal	350mg/kg (350mg/kg)		Chemical and Pharmaceutical Bulletin. Vol. 8, Pg. 807, 1960.