Carbonylation of β-Aminoethanols, Diols, and Diol Amines

Article abstract of DOI:10.1021/jo00365a024

Oxazolidinones are prepared from the palladium-catalyzed carbonylation of β-aminoethanols under mild conditions.With N-alkyl-substituted substrates, conditions for double carbon monoxide incorporation to give morpholinediones have been discovered.Cyclic carbonates can be prepared from the carbonylation of diols.The carbonylation of N-phenyl-1-aminopropane-2,3-diol can give either the carbonate or oxazolidinone as the major product depending on the reaction conditions.