Tetrahedron Letters p. 5623 - 5626 (1985)
Update date:2022-08-02
Topics:
Hanessian, Stephen
Murray, Peter J.
Sahoo, Soumya P.
A synthetic sequence is described wherein a chiral butyrolactone is used as a template to control the stereochemistry of a C-methylation process on the corresponding enolate.A sequential two-carbon homologation and replication of the butyrolactone template allows a second stereocontrolled C-methylation.The ultimate outcome is a seven carbon acyclic chain with a predicable 1,5-substitution pattern of C-methyl groups with or without an intervening hydroxyl group.
View MoreJiaxing Anrui Material Technology Co., Ltd.
Contact:86-573-82651652 13305832579
Address:Room 407, Technology Building, 1369 Chennan Road, Jiaxing City, Zhejiang, China
Shao Xing Empire Import&Export CO.,ltd
Contact:86-575-82127757
Address:11#, Weiwu Road, Shangyu Industrial Park, Hangzhou Bay, Hangzhou, Zhejiang Province, China
Jinan Xinke Pharmaceutical Science and Technology Co., Ltd.
Contact:+86 13256107535
Address:No. 592 the first gangxing road
Hubei Danao Pharmaceutical Co.,Ltd.
website:http://www.danaopharm.com
Contact:+86-719-5251167
Address:Fandan Road,Danjiangkou,Hubei
Nanjing Fubang Chemical Co.,Ltd
Contact:+86-25-83179199
Address:5F,Tianzheng international plaza,No399 Zhongyang Road ,Nanjing China
Doi:10.1021/jo01150a004
(1950)Doi:10.1021/ja01516a038
(1959)Doi:10.1016/j.tet.2008.01.011
(2008)Doi:10.1016/j.tet.2008.01.010
(2008)Doi:10.1016/j.molcata.2016.08.012
(2016)Doi:10.1021/ol800063d
(2008)
