An efficient synthesis of pyrazolo[3,4- b]quinolin-3-amine and benzo[b][1,8]naphthyridine derivatives

Article abstract of DOI:10.3390/12030361

2-Oxo-4-phenyl-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile (10) reacted with hydrazine hydrate, phenylisothiocyanate or benzoyl chloride to give derivatives 12, 13 and 15, respectively. The latter two products were treated with hydrazine hydrate to affo