
Tetrahedron p. 3917 - 3922 (1987)
Update date:2022-08-03
Topics:
Ueda, Taisei
Shibata, Yoshitugu
Kato, Yuzo
Sakakibara, Jinsaku
3,4-Disubstituted isothiazoles (8a,b, 9a,b, 10, 11, 14a,b) were synthesized from 5-amino-6-methyl-4(3H)-pyrimidinone (1) or 1,3-disubstituted 5-amino-6-methyluracils (12a,b) via the formation of isothiazolo<4,3-d>pyrimidines (6, 13a,b) followed by the rea
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