LACTAMS OF ACETALS AND ACID AMIDES. 45. SYNTHESIS OF CONDENSED 2-PYRIDONES FROM ACTIVATED AMIDES, LACTAMS, AND LACTONES

Article abstract of DOI:10.1007/BF00519144

By reaction of lactim ethers with N-substituted cyanoacetamides, the corresponding enaminoamides were obtained, cyclization of which by dimethylformamide acetal gave derivatives of pyrrolo<3,2-c>pyridine, 1,6-naphthyridine, and pyrido<4,3-b>azepine, having a substituent at the nitrogen atom of the pyridone ring.N-substituted furo<3,2-c>pyridines were synthesized from the diethyl acetals of butyrolactone and 3-(dimethylaminomethylene)butyrolactone and dimethylformamide acetal.