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Synthetic study of 1-substituted carbapenem antibiotics

DOI: 10.1016/S0040-4039(00)94938-4

Source and publish data:

Tetrahedron Letters p. 4739 - 4742 (1985)

Update date:2022-07-29

Topics:

Authors:

ShibataShibata

IinoIino

TanakaTanaka

et al.et al.

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Article abstract of DOI:10.1016/S0040-4039(00)94938-4

Total synthesis of 1-substituted carbapenems is described. The key step is the reaction of acetoxyazetidinone with ketene silyl acetal.

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Full text of DOI:10.1016/S0040-4039(00)94938-4

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Product name:2-{(2S,3S)-3-[1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-methyl-thiopropionic acid S-p-tolyl ester

Cas No:101765-72-4

101765-72-4

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