Synthesis of 2-Trifluoromethyl-1,3-cyclopentanedione and 2-Trifluoromethyl-1,4-benzoquinone via Chlorous Acid Oxidation of 3-Trifluoromethylphenol

DOI: 10.1055/s-1985-31445

Source and publish data:

Synthesis p. 1120 - 1121 (1985)

Update date:2022-07-30

Topics:

Authors:

Blazejewski, Jean-Claude

Dorme, Regine

Wakselman, Claude

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Article abstract of DOI:10.1055/s-1985-31445

A new synthesis of 2-trifluoromethyl-1,4-benzoquinone and 2-chloro-2-trifluoromethyl-1,3-cyclopentanedione by oxidation of 3-trifluoromethylphenol with sodium chlorite/sulfuric acid (chlorous acid) is described.In addition, the hydrodechlorination of 2-chloro-2-trifluoromethyl-1,3-cyclopentanedione to give 2-trifluoromethyl-1,3-cyclopentanedione by hydroiodic acid (generated in catalytic amounts from iodine and thiophenol) has been achieved.

Full text of DOI:10.1055/s-1985-31445

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