Journal of Organic Chemistry p. 3589 - 3592 (2008)
Update date:2022-08-04
Topics:
Sang, Yingxia
Zhao, Jingrui
Jia, Xueshun
Zhai, Hongbin
(Chemical Equation Presented) (+)-Pyrido[3,4-b]homotropane (PHT) was efficiently constructed in 12 steps from N,N-diisopropylisonicotinamide. The synthesis features (i) RCM reaction in installing the homotropane skeleton, (ii) Snieckus ortho-lithiation of
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