SYNTHESIS OF UVARETIN, AN ANTITUMOUR AND ANTIMICROBIAL FLAVONOID

Article abstract of DOI:10.1016/S0040-4039(00)94957-8

The flavonoid uvaretin (1-(2,4-dihydroxy-6-methoxy-3-((2-hydroxyphenyl)-methyl)-phenyl)-3-phenyl-1-propanone), known to be active against some tumours and several bacteria, has been synthesized in six steps from 2',4',6'-trimethoxyacetophenone, 2-hydroxybenzaldehyde and benzaldehyde.