Synthesis and reactivity of β-amino α,β-unsaturated ketones and esters using K-10 montmorillonite

Article abstract of DOI:10.1055/s-1994-25595

A series of β-amino α,β-unsaturated ketones 3a-f and esters 3g-l may be conveniently prepared by dispersing ammonia (NH₄OH solution), primary amines and 1,3-diketones or 1,3-keto esters on K-10 montmorillonite without solvent. This procedure was also applicable to the reactions of 3a and 3g with phenyl isocyanate and phenyl isothiocyanate which afford selectively the C-adducts 4a-d.