Synthesis of 2-fluoro- acids, esters, and amides from α-dicyanoepoxides

Article abstract of DOI:10.1080/00397919608003723

The opening of α-dicyanoepoxides by pyridine polyhydrofluoride yields polymerisable 2-fluorocyanoformyls which may be kept intact when diluated in dichloromethane or ether. These intermediates react with nucleophiles such as water, methanol or amines to give respectively 2-fluoroacids, esters or amides.

Full text of DOI:10.1080/00397919608003723

This article was downloaded by: [130.132.123.28]
On: 30 September 2014, At: 06:10
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number:
1072954 Registered office: Mortimer House, 37-41 Mortimer Street,
London W1T 3JH, UK
Synthetic Communications:
An International Journal
for Rapid Communication of
Synthetic Organic Chemistry
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/lsyc20
Synthesis of 2-Fluoro- Acids,
Esters, and Amides From Ã-
Dicyanoepoxides
A. Ould Amanetoullah a , M. M. Chaabouni b &
A. Baklouti a
a Laboratoire de Chimie Structurale Organique,
Faculté des Sciences de Tunis , Campus
Universitaire , 1060, Tunis, Tunisie
b Ecole Superieure des Industries Alimentaires ,
58 Alain Savary, 1003, Tunis, Tunisie
Published online: 21 Aug 2006.
To cite this article: A. Ould Amanetoullah , M. M. Chaabouni & A. Baklouti
(1996) Synthesis of 2-Fluoro- Acids, Esters, and Amides From Ã-Dicyanoepoxides,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 26:6, 1155-1161, DOI: 10.1080/00397919608003723
To link to this article: http://dx.doi.org/10.1080/00397919608003723
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all
the information (the “Content”) contained in the publications on our
platform. However, Taylor & Francis, our agents, and our licensors
make no representations or warranties whatsoever as to the accuracy,
completeness, or suitability for any purpose of the Content. Any opinions
and views expressed in this publication are the opinions and views of

the authors, and are not the views of or endorsed by Taylor & Francis.
The accuracy of the Content should not be relied upon and should be
independently verified with primary sources of information. Taylor and
Francis shall not be liable for any losses, actions, claims, proceedings,
demands, costs, expenses, damages, and other liabilities whatsoever
or howsoever caused arising directly or indirectly in connection with, in
relation to or arising out of the use of the Content.
This article may be used for research, teaching, and private study
purposes. Any substantial or systematic reproduction, redistribution,
reselling, loan, sub-licensing, systematic supply, or distribution in any
form to anyone is expressly forbidden. Terms & Conditions of access
and use can be found at http://www.tandfonline.com/page/terms-and-
conditions