Iodine-promoted synthesis of acylindolizine derivatives from acetylenecarboxylates and pyridinium, isoquinolinium, or quinolinium ylides

Article abstract of DOI:10.1007/s00706-013-1120-6

An iodine-promoted synthesis of acylindolizinecarboxylates via 1,3-dipolar cycloaddition of nitrogen ylides with acetylenecarboxylates and subsequent aromatization for the generation of a wide range of structurally interesting, pharmacologically and photoelectrically significant compounds is reported. Only readily available materials, mild conditions, and operationally trivial reaction protocols were required. Graphical abstract: [Figure not available: see fulltext.]