Oxymetalation of Khellin. Solvomercuration, Osmylation, and Palladium-Catalyzed Oxidation of the Furan Ring in Khellin. The Synthesis of Highly Oxygenated Chromones and 2-Substituted Furochromones

Article abstract of DOI:10.1021/jo00366a007

Oxidation of khellin with thallium(III) nitrate (TTN) in methanol results in the addition of two molecules of methanol across the 2,3-double bond in the furan ring.Oxidation of khellin with mercuric(II) nitrate (Hg(NO3)2) in aqueous THF followed by treatm