Journal of Medicinal Chemistry p. 1769 - 1776 (1986)
Update date:2022-07-30
Topics:
Atwell, Graham, J.
Baguley, Bruce C.
Finlay, Graeme J.
Rewcastle, Gordon W.
Denny, William A.
Replacement of the 3'-methoxy group of the clinical antileukemic agent amsacrine (1) with a 3'-methylamino group provides a compound (3) with a broader spectrum of action, including in vivo activity against experimental solid tumors.The synthesis, physico
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