Synthesis of Unsaturated Acids by 1,2-Addition of Formic Acid to Conjugated Dienes Catalyzed by Palladium on Carbon in the Presence of Mono and Bidentate Phosphines

Article abstract of DOI:10.1016/S0040-4039(00)73391-0

Di-, and trisubstituted 1,3-dienes are converted to γ,δ-unsaturated acids by use of formic acid, carbon monoxide, and catalytic quantities of Pd-C/PPh3/Ph2P(CH2)4PPh2 in 1,2-dimethoxyethane.A β,γ-unsaturated acid was obtained when the monosubstituted diene, isoprene, was used as the reactant.