Renin inhibitors containing ψ[CH2O]pseudopeptide inserts

DOI: 10.1021/jm00398a029

Source and publish data:

Journal of Medicinal Chemistry p. 671 - 677 (1988)

Update date:2022-07-30

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Authors:

TenBrink

Pals Pals

Harris Harris

Johnson Johnson

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Article abstract of DOI:10.1021/jm00398a029

Renin inhibitors 2-4 with the D-Lys renin inhibitory peptide (RIP) sequence, but containing Leuψ[CH₂O]Ala (2), Leuψ[CH₂O]Val (3), and Leuψ[CH₂O]Leu (4) at the P₁-P₁' site, were of a comparable potency

Full text of DOI:10.1021/jm00398a029

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