4710
G. Besong et al. / Tetrahedron 64 (2008) 4700e4710
1332 m, 1229 s, 1146 m, 1089 s, 1057 m, 1005 m, 820 m cmꢀ1
.
26. Suzuki, A. Handbook of Organopalladium Chemistry for Organic Synthe-
sis; Negishi, E.-i., de Meijere, A., Eds.; Wiley-Interscience: 2002; Vol. 1,
pp 249e262; Kotha, S.; Lahiri, K.; Kashinath, D. Tetrahedron 2002, 58,
9633e9695.
LRMS (ESþ): m/z 299 [MþꢀNH3Cl, 100%], 316 [MþꢀCl,
96%], 317 (25), 285 (50). HRMS (ESþ): found: 316.1555.
C18H22NO4 (MþH) requires: 316.1549.
27. Bolton, R. E.; Moody, C. J.; Pass, M.; Rees, C. W.; Tojo, G. J. Chem. Soc.,
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28. (a) For preceding uses of the Suzuki coupling in the synthesis of colchi-
cinoids see: Banwell, M. G.; Cameron, J. M.; Collis, M. P.; Crisp,
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Joncour, A.; Decor, A.; Thoret, S.; Chiaroni, A.; Baudoin, O. Angew.
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Acknowledgements
We thank AstraZeneca (Alderley Edge) for financial
support and James Titchmarsh for chiral HPLC analyses.
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