
Chemistry of Heterocyclic Compounds p. 1034 - 1039 (1985)
Update date:2022-09-26
Topics:
Dovgilevich, A. V.
Zelenin, K. N.
Espenbetov, A. A.
Struchkov, Yu. T.
Bezhan, I. P.
et al.
It was shown by x-ray diffraction analysis and PMR spectroscopy that 1-acyl-5-hydroxy- and -5-hydrazinopyrazolidines have a conformation with an axial orientation of the functional group attached to the C(5) atom.The 1-salicylyl derivatives constitute an exception: in methanol solutions they exist in a conformation with an equatorial hydroxy group, whereas in dimethylformamide (DMF) the ring undergoes partial opening to give the corresponding β-hydrazido aldehydes.
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