
Tetrahedron Letters p. 5683 - 5684 (1985)
Update date:2022-08-04
Topics:
Dana, Gilbert
Figadere, Bruno
Touboul, Estera
Hydroboration of β acetylenic alcohols followed by NaOH/H2O2 oxidation leads to hemiacetals of γ aldols which are easily dehydrated to 2,3-dihydrofuran compounds.The reaction gives good yields with hindered alcohols and its stereochemistry may be controlled during the organometallic synthesis of the starting alcohol.
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