ASYMMETRIC SYNTHESIS OF β-SUBSTITUTED ALCANOIC ACIDS VIA HIGHLY STEREOSELECTIVE CONJUGATE ADDITIONS OF ORGANOCOPPER COMPOUNDS TO CHIRAL ENOATES

DOI: 10.1016/S0040-4039(00)95122-0

Source and publish data:

Tetrahedron Letters p. 6051 - 6054 (1985)

Update date:2022-07-30

Topics:

Authors:

Helmchen, Guenter

Wegner, Guenter

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Article abstract of DOI:10.1016/S0040-4039(00)95122-0

Conjugate additions of organocopper compounds RCu*BF3 to enoates of sulfonamide-shielded alcohols 1x and 1n quite generally proceed with >99percent ee and >90percent yield.

Full text of DOI:10.1016/S0040-4039(00)95122-0

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